The samples of the small intestine were collected on days 0 and 28 for the determination of intestinal morphology and integrity. Intestinal morphological measurements included the following indices: villus height (VH), crypt depth (CD), and VH:CD. The mean values of VH, CD, and their ratio w...
Israel, E. J. et al. Expression of the neonatal Fc receptor, FcRn, on human intestinal epithelial cells. Immunology 92, 69–74 (1997). Article PubMed PubMed Central CAS Google Scholar Kotloff, K. L. et al. Burden and aetiology of diarrhoeal disease in infants and young children in ...
Altered intestinal microbiota composition in old age is associated with chronic low-grade inflammation and increasing susceptibility to age-associated chronic diseases. However, whether age-associated changes in the diversity, composition, or function of the gut microbiota are causal in disease etiology re...
There is considerable interest in the effects of the intestinal microbiota (IM) composition, its activities in relation with the metabolism of dietary subs
Comparison of the intestinal bacterial communities at the OTU level by LEfSe: A comparison of the bacterial communities in the intestinal contents between the control and vaccinated groups, B comparison of the bacterial communities in the intestinal mucosae between the control and vaccinated groups. Th...
Our evolving understanding of intestinal microbiota-derived physiological modulators (e.g., short-chain fatty acids) and pathogenic mediators (e.g., trimethylamine N-oxide) of host disease susceptibility have created novel potential therapeutic opportunities for improved cardiovascular health. This review ...
E. coli expansion significantly increased the concentration of LPS in the intestinal lumen (post hoc Dunnett’s test, p-value < 0.001) (Fig. 4g) and the expression of IOD1 in colonic tissue (post hoc Dunnett’s test, p-value < 0.001) (Fig. ...
the integrity of the intestinal barrier [14]. Interestingly, TNFSF15 encoding the TLA1 protein is identified in both Crohn´s disease and IBS [15, 16•], underlining the pos- sibility of common pathways in these diseases. Cells of the immune system have specific receptors, for ...
We analyzed gut microbiota in DLB to examine whether any intestinal bacteria are unique to DLB, as well as to both DLB and PD with cognitive decline (PDD+). Analysis of each taxon between DLB and controls revealed that seven genera (Agathobacter,Lachnospiraceae ND3007 group,Butyricicoccus,Copr...
It is noteworthy that PPARα, by mediating signals received from the microbiota via toll-like receptors (TLR), contributes to both the circadian expression of genes in the intestine and intestinal corticosterone production [75]. Thus, PPARα mediates signals from the GI flora, which impact the ...