El peso de la microbiota intestinal es entre 1,5 y 2 kilos y está compuesta de más de 1000 especies diferentes de bacterias. En los últimos años se están produciendo grandes avances que aportan una nueva perspectiva al papel del microbioma intestinal en la salud y la capacidad que...
Despite the abundant presence of HDAC inhibitors such as butyrate in the intestine, we found that HDAC3 activity was sharply increased in intestinal epithelial cells of microbiota-replete mice compared with germ-free mice. This divergence was reconciled by the finding that commensal bacteria, ...
The intestinal epithelial barrier prevents microbial entry into the circulatory system under stable conditions. Dendritic cells, however, can actively penetrate the epithelium, sample microbes from the gut lumen (74) and possibly trans- port the bacteria to the placenta (Figure 3). Interestingly, ...
Increased oral detection, but decreased intestinal signaling for fats in mice lacking gut microbiota. PLoS One. 2012;7(6):e39748. 38. Breton J, Tennoune N, Lucas N, Francois M, Legrand R, Jac- quemot J, et al. Gut commensal E. coli proteins activate host satiety pathways following ...
intestinal microbiota and the host. Bacterial cells by far outnumber the host cells, harbor millions of genes and form a community termed the microbiome. Through expression of this amount of genes they can execute numerous enzymatic reactions that the host is not able to catalyze. As a consequen...
For the first time, this study analyses the composition and diversity of the gut microbiota of Isostichopus badionotus in captivity, using high-throughput
ablation, the resistance of the intestinal microbiota of the ETEC-infected mice to bacteria was significantly reduced, and the level of inflammation was increased, showed the intestinal microbiota plays an important role in maintaining immune resistance, high doses of stachyose can promote and restore...
Mascaraque, O. Martínez-Augustin Intestinal inflammation and mucosal barrier function Inflammatory Bowel Diseases, 20 (2014), pp. 2394-2404 Google Scholar Sartor, 2006 R.B. Sartor Mechanisms of disease: Pathogenesis of Crohn's disease and ulcerative colitis Nature Reviews Gastroenterology and ...
Abstract Human-associated microbial communities have adapted to environmental pressures. Doses of antibiotics select for a community with increased antibiotic resistance, inflammation is accompanied by expansion of community members equipped to flourish in the presence of immune effectors and Western diets sh...
Complex microbial communities inhabit vertebrate digestive systems but thorough understanding of the ecological dynamics and functions of host-associated microbiota within natural habitats is limited. We investigate the role of environmental conditions i