Alkanes, the major constituents of gasoline, diesel, and jet fuel, are naturally produced by diverse species; however, the genetics and biochemistry behind this biology have remained elusive. Here we describe the discovery of an alkane biosynthesis pathway from cyanobacteria. The pathway consists of ...
Microbial biosynthesis of alkanes. Science, 2010, 329: 559-562.Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB. 2010. Micro- bial biosynthesis of alkanes. Science 329:559 -562.Schirmer, A., M. A. Rude, ...
B. Microbial biosynthesis of alkanes. Science 329, 559–562 (2010). Article CAS PubMed Google Scholar Rude, M. A. et al. Terminal olefin (1-alkene) biosynthesis by a novel p450 fatty acid decarboxylase from Jeotgalicoccus species. Appl. Environ. Microbiol. 77, 1718–1727 (2011). ...
B. Microbial biosynthesis of alkanes. Science 329, 559–562 (2010). A report describing the alkane-producing pathway in cyanobacteria, including an acyl-ACP reductase and an aldehyde decarbonylase, which together convert fatty acyl-ACP to alkanes and alkenes. When introduced into E. coli , ...
Microbial biosynthesis of alkanes. Science. 2010;329(5991):559–62. Article CAS Google Scholar Zheng YN, Li LL, Liu Q, Yang JM, Wang XW, Liu W, et al. Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered...
Rutter CD, Zhang S, Rao CV (2015) Engineering Yarrowia lipolytica for production of medium-chain fatty acids. Appl Microbiol Biotechnol 99:7359–7368 Article CAS Google Scholar Schirmer A, Rude MA, Li X, Popova E, Del Cardayre SB (2010) Microbial biosynthesis of alkanes. Science 329:559–...
Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB: Microbial biosynthesis of alkanes. Science. 2010, 329: 559-562. 10.1126/science.1187936. Article CAS Google Scholar Mutalik VK, Guimaraes JC, Cambray G, Lam C, Christoffersen MJ, Mai QA, Tran AB, Paull M, Keasling JD, Arkin ...
Advanced biofuels produced by microorganisms have similar properties to petroleum-based fuels, and can 'drop in' to the existing transportation infrastructure. However, producing these biofuels in yields high enough to be useful requires the engineering of the microorganism's metabolism. Such engineering...
Rare earth elements (REEs) are essential raw materials vital for the advancement of modern high-tech industries. However, their extraction often leads to e
(FabH)(1), which is inhibited by unsaturated fatty acyl-ACPs(2), was enhanced to promote the initiation of fatty acid biosynthesis by deleting the fadR gene; deletion of the fadR gene prevents upregulation of the fabA and fabB genes responsible for unsaturated fatty acids biosynthesis(3)....