The importance of the gut-lung axis has become more evident following the identification of several gut microbe-derived components and metabolites, such as short-chain fatty acids (SCFAs), as key mediators for setting the tone of the immune system. Recent studies have supported a role for SCFAs...
Table S5. Gut microbiota significantly more abundant across future neurodevelopmental disorder (ND) cases compared to controls, related to Figure 5 Table S6. Other stool metabolites with differential expression between future autism spectrum disorder (ASD) cases and controls (n = 46), related to Fig...
Microbiota‐gut‐brain axis: Interaction of gut microbes and their metabolites with host epithelial barriers 来自 Wiley 喜欢 0 阅读量: 137 作者: Y Bhattarai 摘要: The gastrointestinal barrier and the blood brain barrier represent an important line of defense to protect the underlying structures ...
we summarize recent studies investigating the crosstalk between gut-innervating neurons, resident immune cells, and epithelial cells at homeostasis and during infection, food allergy, and inflammatory bowel disease. We introduce the neuroanatomy of the gastrointestinal...
Recent advances have provided scientific evidence that CVD may also be attributed to gut microbiome. In this review, we highlight the complex interplay between microbes, their metabolites, and the potential influence on the generation and development of CVDs. The therapeutic potential of using ...
gutMGene (http://bio-annotation.cn/gutmgene), a manually curated database, aims at providing a comprehensive resource of target genes of gut microbes and microbial metabolites in humans and mice. Metagenomic sequencing of fecal samples has identified 3.3 × 106 non-redundant microbial genes from...
Bidirectional interactions through secretory metabolites of the gut microbiota impact CS in intestinal cells. Some gut microbiome metabolites are known to exert strong anti-inflammatory and antioxidant effects, that may affect the functioning of distal organs and systems, in turn potentially attenuating ...
Moreover, androgenic ring-cleaved metabolites were detected in the fecal extracts of the strain GDN1-administered mice. Furthermore, our RT – qPCR results revealed the expression of the androgen catabolism genes in the gut of the strain GD...
摘要:Cholestasis refers to impaired bile flow from the liver to the intestine. In neonates, cholestasis causes poor growth and may progress to liver failure and death. Normal bile flow requires an intact liver-gut-microbiome axis, whereby l...
microbes, metabolites, and the gut-lung axisThe microbiota plays an essential role in the education, development, and function of the immune system, both locally and systemically. Emerging experimental and epidemiological ev... 查看全部>>doi:10.1038/s41385-019-0160-6Anh Thu Dang...