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Scherf U, Ross DT, Waltham M, Smith LH, Lee JK, Kohn KW, Reinhold WC, Myers TG, Andrews DT, Scudiero DA, Eisen MB, Sausville EA, Pommier Y, Botstein D, Brown PO, Weinstein JN: A cDNA microarray gene expression database for the molecular pharmacology of cancer. Nature Genetics. 200...
Results: We have developed a new bioinformatics tool called MGFM (Marker Gene Finder in Microarray data) to predict marker genes from microarray gene expression data. Marker genes are identified through the grouping of samples of the same type with similar marker gene expression levels. We ...
Gene expression databases are key resources for microarray data management and analysis and the importance of a proper annotation of their content is well understood. Public repositories as well as microarray database systems that can be implemented by single laboratories exist. However, there is not...
The Gene Expression Omnibus (GEO) at the National Center for Biotechnology Information (NCBI) has emerged as the leading fully public repository for gene expression data. This chapter describes how to use Web-based interfaces, applications, and graphics
Results: We have developed a new bioinformatics tool called MGFM (Marker Gene Finder in Microarray data) to predict marker genes from microarray gene expression data. Marker genes are identified through the grouping of samples of the same type with similar marker gene expression levels. We ...
This paper presents a novel two-stage evolutionary strategy for gene feature selection combining the genetic algorithm with biological information extracted from the KEGG database. A comparative study is carried out over public data from three different types of cancer (leukemia, lung cancer and ...
The results obtained in the three experiments were consistent and reported the same changes in gene expression between the schizophrenic and control subject (data not shown). These control data indicated that microarray analysis is a reliable tool for analyzing gene expression changes in human ...
databaseformicroarray geneexpressiondata HelenParkinson MicroarrayInformaticsTeam EuropeanBioinformaticsInstitute Transcriptome2002,Seattle TheEuropeanBioinformaticsInstitute Whyhaveapublicdatabase? Easydataaccess Resolveslocalstorageissues Commondataexchangeformatscanbe developed Improveddatacomparison Curationcanbeapplied Annot...
The advantage of using a comprehensive database in the probe remapping was demonstrated as more genes and more alternative splicing events are detected. Using two different zebrafish gene expression experiments, we show the benefits of using the more comprehensive remapping and confirm the improvement ...