regardless of sex chromosome genotype, while males of each genotype had higher energy expenditure than females (Fig.1d–f). Moreover, XX mice with higher body weights and fat mass had significantly higher food intake (male and female, Fig.1d;P = 0.028, 2-way ANOVA with Holm–Sidak te...
A&A in mice may constitute a major part of the problem with laboratory animal anesthesia. There are at least three invaluable papers [6,7,13] with a detailed discussion of A&A in mice. However, these
Sudden death may result or subacute illness associated with one or more of the following signs may develop: ruffled fur, hunched posture, motionlessness, and neurological deficits. Mice suspended by the tail display coarse tremors of the head and extremities, culminating in clonic convulsions and ...
In rodents, males consuming HFD develop obesity associated with a hypothalamic injury response that includes increased microglial activation and inflammatory signalling3,4. In contrast, female mice are more DIO resistant5,6, but their hypothalamic responses to HFD have been largely uncharacterized. To d...
In contrast, enterotropic MHV strains (e.g. LIVIM, MHV-D, MHV-Y) tend to selectively infect intestinal mucosal epithelium, with no or minimal dissemination to other organs such as mesenteric lymph nodes or liver. All ages and strains are susceptible to active infection, but disease is ...
Located in the Southwestern US, these mice have shorter, nearly hairless tails. They have a dark grey-brown back and grey sides, making them fairly easy to spot. The body generally grows to between 2 and 2.5 inches with a tail length of 1.5 to 1.75 inches. ...
her a prisoner with promises of a suburban life to come. However, she is no different than He in the lab, being fed reluctantly on occasion by her “keeper” (Oates1994, 297). Her martyrdom takes the form of multiple rapes by strangers as her cruel husband watches with sadistic pleasure...
2B and C, the body weight (BW) and BW gain of the Model group were significantly increased compared with those of the NC group, but there was no significant difference between the treatment groups and the Model group. Interestingly, the liver weight index (liver weight/BW) was significantly...
Tail suspension test (TST) Each mouse was suspended with adhesive tape affixed 1–2 cm to the tip of the tail and inverted for 6 min, with its nose 20–25 cm away from the ground. Immobile state was considered as no body movement and passive hanging. The ratio of immobility was quantif...
46, showed that females had worse gnawing behavior in the 4NQO tongue cancer model compared to males whereas we observed no difference in pain behaviors in the current study with HSC3 tongue tumors (Fig S1). Nonetheless, our data has clinical implications as it is crucial to understand the ...