Microglial cell extraction was performed as previously described using methods that have been widely validated for obtaining a resting microglial profile67,68. Briefly, cohorts of female (n=8 per group) and male mice (n=16 per group) were placed on chow or HFD for 3 months. After perfusion ...
WT and Flox (loxP) sequences with Cre expression were considered hemizygous for menin in the liver (HETs).4 All experiments were conducted with WT HFD N ¼ 7 and HET HFD N ¼ 5 unless otherwise noted. Serum hormone assays and glucose tolerance test Fasting glucose was obtained using a...
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N is the total number of mice included in each genotype. The black line is the survival curve of the Mecp2 mutant (Mecp2KO) mice. The dashed line is the survival curve of the Mecp2+/y;cre93;Bdnf2lox/2lox (BdnfKO) mice. The medium gray line is the survival curve of the Mecp...
(Additional file1: Fig. S2G–I). The N-acetylaspartate level was increased in the Model group and decreased in the XKY-H treatment group (Additional file1: Fig. S2J). In the phenylalanine, tyrosine and tryptophan biosynthesis pathway,L-Tryptophan and L-Tyrosine levels were decreased in the...
and species abundance of the 10 more abundant taxa in the cecum ofdb/dbmice treated with vehicle orO. laneus(d) (n= 15). mRNA expression levels of inflammatory genes in the scWAT, vWAT, liver, and intestine (e) (n= 7–10). Data are presented as mean + s.e.m. *p< 0.05; **p...
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To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/. Reprints and permissions About this article Cite this article Moon, N., Morgan, C.P., Marx-Rattner, R. et al. Stress increases sperm respiration and motility in mice and men. Nat Commun 15, ...
The mitochondrial Ahi1/GR participates the regulation on mtDNA copy numbers and brain ATP levels and modulates depressive behaviors in mice. Cell Commun. Signal. 21, 21 (2023). Article CAS PubMed PubMed Central Google Scholar Li, J., King, N. C. & Sinoway, L. I. Interstitial ATP and...