humans they become forgetful. By the time these mice are seven months old they are unable to remember, for example, which pan of a maze they have explored before. Two months later, their brains are filled with protein "plaques" that also characterise the latter stage of the disease in ...
In the Shock Start condition the CBA strain showed only a suppressed alternation, while the NZB strain administered the same treatment perseverated. Both strains perseverated in the Shock Choice condition. In Experiment 2, NZB mice administered identical shocks in the start box and goal arms on ...
In fact, while learning, thedeveloped than other mice's.mice that waited 30 seconds between trips soonD. Because the maze they enteredbecame the best at finding the chocolate, but thosewas simpler than the first maze.that waited an hour improved the least.The experiment shows that takingBut ...
Since there were no marked sex differences in the initial precipitated withdrawal experiment, only males were used for subsequent studies to reduce the number of animals used. Individual data points on each figure denote number of mice in each condition. Mice were housed in groups of 4–5 in ...
But water maze tests demonstrated that the treated mice could distinguish infrared patterns while also exposed to daylight. In fact, mice taught that a certain infrared pattern led to a submerged platform in the water used the same rule when the pattern was displayed in the visible light...
In the tail suspension test, open field test and elevated plus maze test, equipment was cleaned with 75% ethanol after every trial in order to minimize scents of the former test object. All the mice testing order was random. Sucrose preference test (SPT) The SPT was performed based on the...
Hippocampal place cells represent the position of a rodent within an environment. In addition, recent experiments show that the CA1 subfield of a passive observer also represents the position of a conspecific performing a spatial task. However, whether this representation is allocentric, egocentric or...
Supplementary Figure 5 Partial loss of miR-137 results in impaired spatial learning and memory. a–d, In the Morris water maze test, Mir137+/– mice (n = 13 mice) exhibited learning and memory deficits in the Morris water maze test. (a) During the training phase, in which four tr...
A maze learning experiment was conducted on a group of nine pairs of mice exposed to noise of 109 dBA for 15 min, over 7, 14 or 21 trials, with one trail each day. The experiment was repeated with equal number of mice in a relatively quiet condition (<44 dBA). Time taken (sec) ...
In another experiment, mice made tolerant to CP also exhibited a cross-tolerance to N 2 O. These results support the hypothesis that the anxiolytic effect of N 2 O is mediated by BZ receptors. 展开 关键词: Nitrous oxide Chlordiazepoxide Flumazenil Benzodiazepine receptors Elevated plus maze Mouse...