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In Experiment 1, mice were trained on a response, a direction or one of two place problems to locate a hidden platform in a water T-maze located in two positions. In the response task, mice made a right (or left) turn from two different start points located 180掳 apart. In the ...
In experiments designed to investigate the relationship between stress and the acquisition of new fear memories, it was found that previous exposure to a r... Manzanares,AR P. - 《Journal of Neuroscience》 被引量: 377发表: 2005年 Effects of mecamylamine on avoidance conditioning and maze lear...
Genetic differences in the tail-suspension test and its relationship to imipramine response among 11 inbred strains of mice Background: The tail suspension test (TST) is a simple screening test for the behavioral effects of antidepressants in rodents. This experiment investigate... X Liu,HK Gershen...
In the tail suspension test, open field test and elevated plus maze test, equipment was cleaned with 75% ethanol after every trial in order to minimize scents of the former test object. All the mice testing order was random. Sucrose preference test (SPT) The SPT was performed based on the...
Spontaneous alternation in a T maze was studied as a one trial learning paradigm in mice of the BALB/c strain. In the first experiment the combined effects of time interval between the first and second trial (intertrial interval: ITI), food deprivation and feeding given during the first trial...
Since there were no marked sex differences in the initial precipitated withdrawal experiment, only males were used for subsequent studies to reduce the number of animals used. Individual data points on each figure denote number of mice in each condition. Mice were housed in groups of 4–5 in ...
(TCM1,TCM2,and TCM3) extract orally were established.A normal group treated with an equal volume of distilled water was also established.Water maze test was adopted to determine the changes in memory of the mice before and after the experiment.After three months of continuous experiment,the ...
In our experiment, the mice living in a simple standard cage placed in the centre of a large enriched environment only indirectly experiencing the stimulus-rich surroundings (IND) did not display increased adult hippocampal neurogenesis. In contrast, the mice living in and directly experiencing the ...
We recently tested three inbred mouse strains (C57BL/6J, DBA/2J, C3H/HeJ) and two F1 hybrids (B6C3F1/J, C3D2F1/J) in an elevated zero-maze for 3 consecutive days. As measured by the latency to enter an open quadrant and percentage of time spent in the open, anxiety increased ov...