轻或中度肝功能受损的患者,本品每日用量不应超过 40 mg(见【注意事项】)。 【不良反应】 安慰剂对照的高血压治疗临床研究表明替米沙坦的不良事件总发生率为 41.4%,安慰剂为 43.9%,二者类似。这些不良反应呈非剂量依赖性,与患者性别、年龄和种族无关。替米沙坦在患者中用于降低心血管患病率的安全性数据与用于降压治...
Initial dose: 40 mg orally once a day Maintenance dose: 40 to 80 mg orally once a day Comments:Most of the antihypertensive effect is present within 2 weeks; maximum blood pressure reduction at a given dose is generally observed within 4 weeks of starting that dose. ...
同时入院时,AUC的降低范围为6%(剂量为40 mg)至19%(剂量为160 mg)。 使血浆中的浓度3小时后,无论在空腹还是食物上施用药物均等。 妇女的Cmax和AUC分别比男性高3倍和2倍,而浓度无明显影响。 与血浆蛋白结合 - 99.5%,主要与白蛋白和α1糖蛋白结合。 平衡阶段的表观分布平均值为500升。 通过与葡萄糖醛酸缀...
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The usual starting dose of MICARDIS tablets is 40 mg orally once a day. Blood pressure response is dose-related over the range of 20 to 80 mg [see Clinical Studies (14.1)]. Most of the antihypertensive effect is apparent within 2 weeks and maximal reduction is generally attained after 4 ...
40 mg/day PO initially; titrated to 20-80 mg/day PO, depending on response; patients with volume depletion should receive the lower dosage initially, under close supervision Most of the antihypertensive effect is apparent within 2 weeks and maximal reduction is generally attained after 4 weeks Wh...
In controlling high blood pressure, adults may start with 40 mg taken once a day. The dose may be adjusted as per doctor’s order when needed. Nevertheless, the normal dosage does not usually exceed 80 mg a day. The dose is determined by age and weight in children. ...
Define Micardis. Micardis synonyms, Micardis pronunciation, Micardis translation, English dictionary definition of Micardis. n. An angiotensin II receptor blocker drug, C33H30N4O2, used primarily to treat hypertension. American Heritage® Dictionary of
40 mg/12.5 mg oral tablets 80 mg/12.5 mg oral tablets 80 mg/25 mg oral tablets How should I store telmisartan/hydrochlorothiazide? Telmisartan/hydrochlorothiazide should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F ...