之前A structured tumor-immune microenvironment in triple negative breast cancer revealed by multiplexed ion beam imaging发现,特定免疫群体连续募集到肿瘤部位可以解释观察到的患者免疫细胞模式。于是在这个研究中,作者提问:观察到的单个肿瘤内跨区域免疫细胞类型组成的变化是否可归因于不同的浸润阶段?整合两项研究的结...
Multiplexed ion beam imaging by time-of-flight (MIBI-TOF) is a form of mass spectrometry imaging that uses metal labeled antibodies and secondary ion mass spectrometry to image dozens of proteins simultaneously in the same tissue section. Working with the National Cancer Institute's (NCI) Cancer...
Reproducible, high-dimensional imaging in archival human tissue by Multiplexed Ion Beam Imaging by Time-of-Flight (MIBI-TOF)doi:10.1038/s41374-022-00778-8Candace C. LiuM. BosséA. KongAdam KagelR. KindersS. HewittS. BendallMichael Angelo...
225: In-depth characterization of immune cells in preeclampsia using Multiplexed Ion Beam Imaging by Time-of-Flight (MIBI-TOF)doi:10.1016/j.ajog.2019.11.241Shirley GreenbaumMarc BosseAlex BaranskiZumana KhairMike AngeloAmerican Journal of Obstetrics and Gynecology...