Margalit H, Altuvia Y (2003) Insights from MHC-bound peptides. Novartis Found Symp 254:77-90; discussion 91-101, 216-22, 250-2Margalit H,Altuvia Y.Insights from MHC-bound peptides. Novartis Foundation Symposium . 2003MARGALIT H,ALTUVIA Y.Insights from MHC-bound peptides.Novartis ...
The features of peptide antigens that contribute to their immunogenicity are not well understood. Although the stability of peptide-MHC (pMHC) is known to be important, current assays assess this interaction only for peptides in isolation and not in the
Peptide antigens bound to molecules encoded by the major histocompatibility complex (MHC) and presented on the cell surface form the targets of T lymphocytes. This critical arm of the adaptive immune system facilitates the eradication of pathogen-infected and cancerous cells, as well as the product...
Peptides eluted from self MHC class II molecules may yield important clues to T cell epitopes in systemic autoimmunity. 展开 关键词: Reactivity IIBound Peptides Systemic ErythematosusProne DOI: 10.4049/jimmunol.170.4.2229 被引量: 35 年份: 2003 ...
上海玉博生物科技有限公司 主要致力于“anti-mouse MHC class I molecule Kb bound to the peptide SIINFEKL (Kb-SIINFEKL) eBioscience-14-5743-81”的生产销售。多年的“anti-mouse MHC class I molecule Kb bound to the peptide SIINFEKL (Kb-SIINFEKL) eBioscience-
上海玉博生物科技有限公司 主要致力于“anti-mouse MHC class I molecule Kb bound to the peptide SIINFEKL (Kb-SIINFEKL) eBioscience-14-5743-82”的生产销售。多年的“anti-mouse MHC class I molecule Kb bound to the peptide SIINFEKL (Kb-SIINFEKL) eBioscience-
These MHC class I:peptide complexes then exit the ER and reach the plasma membrane, serving to sustain the steady-state MHC class I expression on the cell surface. A novel subset of MHC class I molecules that preferentially bind lipid-containing ligands rather than conventional peptides was ...
Download PDFs Help Help The human cell surface protein CD4 is not only an important accessory molecule in the activation of MHC class-II-restricted T cells, but has also been implicated to be a receptor for the human immunodeficiency virus HIV-I on lymphoid and monocytic cells. We have ...
The present invention relates to novel peptides derived from Homeobox protein Hox-B13 (HOXB13), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bin...
(TAA) and peptides derived from these antigens may be displayed on the tumour cell surface. Detection of a MHC class I-presented TAA-derived peptide by a CD8+ T cell bearing the corresponding T cell receptor, leads to targeted killing of the tumour cell. However, as a consequence of the...