Structure and function of natural killer cell surface receptors. Annu. Rev. Biophys. Biocool. Struct. Google Scholar Wang, J., M.C. Whitman, K. Natarajan, J. Tormo, R.A. Mariuzza, and D.H. Margulies (2002). Binding of the natural killer cell inhibitory receptor Ly49A to its major...
Inference of structure and function of fish Major Histocompatibility Complex (MHC) molecules from ex- pressed genes. Fish Shellfish Immunol 1996;6:305 - 18.Rene J M. Inference of structure and function of fish major histocompatibility complex ( MHC ) molecules from expressed genes. Fish & Shell...
【免疫学】MHC分子的结构与功能(Structure and Function of MHC Molecules) 81 -- 11:48 App 免疫学基础P2W2-MHC分子-6-MHC基因表达 4411 1 6:04 App MHC分子 294 -- 4:30 App MHC||类分子抗原提成途径(本科免疫学) 657 -- 0:48 App 医学免疫学动画丨MHC-II类分子的结构 1.7万 11 7:12 ...
Human MHC Class II Antigens: Genetics, Structure and Function Proceedings of the First International Workshop on Monoclonal Antibodies to Human MHC Class II Antigens Disease Markers (special issue) — Volume 2 Edited by H.M. Dick, C.M. Steel and B. Dupont John Wiley and Sons, Chichester ...
•1960–1970,BenacerrafandMcDevittfoundimmuneresponsegenes(Ir)existinginMHC •ThereisMHCrestrictioninCTLkillingvirus-infectedtargetcells.•ThemainfunctionisantigenpresentationtoTcells,initiatingimmuneresponse.OutlineofLecture •Discovery&conceptsofMHC•Structure&propertiesofMHCGenes•Structure&propertiesofMHC...
Half a century after the major histocompatibility complex (MHC) was discovered, its functional roles in health and disease remain poorly understood. Many hallmarks of the MHC, including its unusual evolution, structure-function properties of its gene products, and allele-specific associations with ...
1.StructureofHLAcomplex A.ClassicalHLAgeneB.GenesassociatedwithimmunefunctionC.CYP21基因(21羟化酶基因)2.ExpressiveproductsofclassⅠgeneandclassⅡgene---HLAmolecules 1.StructureofHLAcomplex A.ClassicalHLAgene ---ClassⅠgeneandClassⅡgene ClassⅡgenes HLAcomplex (HLAⅠagene)classⅠgenes HLA-DP,HLA-...
Proteins: Structure, Function, and BioinformaticsSchueler-Furman O,Altuvia Y,Margalit H.Examination of possible structural constraints of MHC-binding peptides by assessment of their native structure within their source proteins. Proteins . 2001
Invariant chain structure and MHC class II function. Cell 84, 505–507 (1996). Article CAS PubMed Google Scholar Dugast, M., Toussaint, H., Dousset, C. & Benaroch, P. AP2 clathrin adaptor complex, but not AP1, controls the access of the major histocompatibility complex (MHC) class ...
The function of the APCs is to present a peptide derived from the antigen to the T cell. 2、抗原递呈细胞 抗原提呈细胞(antigen-presenting cell,APC)是指能表达被特异淋巴细胞识别的抗原肽:MHC分子复合物的任何细胞(图2-8,图2-9)。 (1)专职抗原提呈细胞:能表达MHC-II类分子的巨噬细胞、树突状细胞...