The banking of human leukocyte antigen (HLA)-homozygous-induced pluripotent stem cells (iPSCs) is considered a future clinical strategy for HLA-matched cell transplantation to reduce immunological graft rejection. Here we show the efficacy of major histocompatibility complex (MHC)-matched allogeneic neur...
Infectious diseases HLA-B*35:01 IPSINVHHY CMV pp65 Pubmed IEDB Scholar Infectious diseases HLA-B*35:01 LPLNVGLPIIGVM CMV UL138 IEDB Scholar Infectious diseases HLA-A*01:01 VTEHDTLLY CMV UL44 Pubmed IEDB Scholar Cancer HLA-A*02:01 SLVDVMPWL Cytochrome p450 1B1 Scholar Cancer HLA-A*24...
Preventing rejection is a major challenge in transplantation medicine, even when using pluripotent stem cell-derived grafts. In iPS cell (iPSC)-based transplantation, to reduce the risk of rejection, it is thought to be optimal that preparing the cells from donors whose human leukocyte antigen-...
另外,在对照细胞而非SUMOi处理细胞的全细胞裂解液中,检测到一个更高分子的抗SAFB反应条带(图6D)。SAFB偶联物在SUMO2/3 IPs中高度富集,但在经过SUMOi处理的样品中完全缺失,这表明它与SUMOylation SAFB相对应(图6D)。为了进一步验证MYC可以诱导SAFB的SUMOylation,SUMOi也可以阻止这种诱导,在对照组细胞和表达MYC...
HiPS-CMs, CD8+ T cell-mediated rejection, NOG MHC double knockout mice, xeno-GVHD, iPS Guo et al. 2024 A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML CD36, AML, MV4-11, T cell, immunosuppression Zhu...
供应造血干细胞培养基,神经干细胞培养基,干细胞无血清培养基,胚胎/IPS干细胞无血清培养基,心肌细胞分化培养基,外周血核型分析培养基。公司立足西南,面向全国,以“积极借鉴成功经验,追求创新”为核心思想,将为客户提供水平的干细胞产品和服务。 “华雅干细胞”是由我们公司的全体员工用心打造的一块金质招牌,我们的...
【4】J Cell Physiol︱华进联团队建立不同细胞来源的猪iPSCs诱导体系并探讨其差异 【5】JCI Insight︱苏文如/郑颖丰团队在眼免疫性疾病的炎症控制和临床靶向防治领域取得新进展 【6】APS 综述︱果德安/吴婉莹团队聚焦天然药物研发中异质性空间分布评述质谱成像技术的作用及研究进展 ...
iPSCs: Induced pluripotent stem cells ITK: Interleukin-2 inducible tyrosine kinase LAK: Lymphokine-activated killer LAT: Linker for activation of T cells LCK: Leukocyte-specific tyrosine kinase LMP2: Latent membrane protein 2 MAGE-A1: Melanoma-associated antigen 1 MAGE-A3: Melanoma-asso...
供应造血干细胞培养基,神经干细胞培养基,干细胞无血清培养基,胚胎/IPS干细胞无血清培养基,心肌细胞分化培养基,外周血核型分析培养基。公司立足西南,面向全国,以“积极借鉴成功经验,追求创新”为核心思想,将为客户提供水平的干细胞产品和服务。 “华雅干细胞”是由我们公司的全体员工用心打造的一块金质招牌,我们的...
二、 任职要求 1、细胞生物学、生命科学等相关专业,硕士或博士学历; 2、有hPSC(iPS或ESC)细胞培养经验,具备多能干细胞来源的类器官诱导经验、具备类器官技术开发、建模经验者优先; 3、具备较强的学习能力和刻苦专研的精神; 4、视野开阔,实时关注相关领域研究的最新动向。