Deletion of Mtor by alpha-MHC-Cre is embryonic lethal.Yi, ZhuKarla, M. P. PiresKevin, J. WhiteheadCurtis, D. OlsenBenjamin, WaymentYi, Cheng ZhangHeiko, BuggerOlesya, IlkunSheldon, E. LitwinGeorge, Thomas
Hac1: a novel yeast bZIP protein binding to the CRE motif is a multicopy suppressor for cdc10 mutant of Schizosaccharomyces pombe. We cloned by phenotypic complementation a novel Saccharomyces cerevlslae's multicopy suppressor of the Schizosaccharomyces pombe cddO-129 mutant which we c... H Nojima...
使用检测人源DR4/小鼠I-E嵌合基因座的存在情况的改良的等位基因检测(Valenzuela等,同上)通过基因分型鉴定携带人源DR4/小鼠I-E嵌合基因座的小鼠。 可以将携带人源DR4/小鼠I-E嵌合基因座的小鼠与Cre基因清除小鼠品系交配(参见例如国际专利申请公开号WO2009/114400)以除去由靶向载体引入的在例如ES细胞阶段或在胚胎中未...
从机制上讲，使用 Trpml3IRES-Cre/eR26-τGFP 报告小鼠模型、转录组学和内溶酶体膜片钳实验，我们表明...
In contrast, when LysM-Cre was used (LysM-Cre CSFR1-DTR mice), pups had decreased Ly6C+ monocytes but the CD206+MHCIIand+ populations were not depleted. These results were confirmed by immunofluorescent staining for CD206 and IBA-1. Thus, we conclude that neonatal intestinal CD206+MHCII...
Compared with control Ldlr(-/-) chimeric mice, CD11c-Cre × Tcf4(-/flox) mice had reduced atherosclerosis levels. To begin to understand the mechanisms by which pDCs regulate atherosclerosis, we studied chimeric Ldlr(-/-) mice with selective MHCII deficiency on pDCs. Significantly, these mice ...
血清Ⅰ类MHc链相关蛋白A、C-反应蛋白、α1-广酸性糖蛋白对恶性妇科肿瘤诊断的临床检测
I-Ab是B6小鼠中表达的MHC II类分子,可以使用F-Ib基因(I-Ab-fl / fl)从Cre表达(Crepos)细胞谱系中阻止。接下来,将B6雄性巢蛋白,绒毛蛋白或Tie2 CreposI-Ab-fl / fl小鼠和相关的CrenegI-Ab-fl / fl小鼠用雌性I-Ab缺乏的骨髓(B6.I-Ab-/- BM)重建,产生缺乏嵌合能力的造血APC呈递BM嵌合体(图S6B–S6D...
As an additional control, we obtained plck-CIITA transgenic mice21, which overexpress MHC II on T cells starting from the DP thymocyte stage (Fig.1e). In the following sections, both strains were analyzed in parallel. For simplicity, we refer to CD4-Cre/Nlrc5-stopfloxas “T-MHC I” mo...
[0291] 77.Creier,Carola,C.C.Investigation of extract influence on antigen presentation in Nef‑expressing dendritic cells and cancer cells.MS thesis.University of Applied Sciences Mannheim,2011 [0292] 78.Sanderson,L.,Taylor,G.W.,Aboagye,E.O.,Alao,J.P.,Latigo,J.R., Coombes,R.C.,Vigus...