receptor β (THR-β) in the liver, while adverse effects, including cardiac effects, are mediated by thyroid hormone receptor α (THR-α). MGL-3196 shows outstanding safety in a rat heart model and is efficacious in a preclinical model at doses that showed no impact on the central thyroid...
英文别名MGL 3196; MGL3196; VIA 3196; VIA3196; VIA-3196;Resmetirom; 分子式C17H12Cl2N6O4分子量435.22 本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。 不同批次的产品详情请咨询我们的客服: 全国免费电话:400-099-8200 在线客服: ...
On the basis of established preclinical and clinical biological activity and safety, resmetirom is being assessed for the treatment of non-alcoholic steatohepatitis with fibrosis in a phase 3 clinical trial. Added value of this study Liver biopsy is an invasive technique with associated morbidity. ...