According to the excitotoxicity hypothesis, a primary factor in the pathogenesis of neuronal damage is the elevated glutamate level in the extracellular space, which causes overstimulation of Glu receptors, primarily the ionotropic N-methyl-D-aspartate (NMDA)-subtype receptor. However, other subtypes o...
Chapter © 2024 Introduction Methamphetamine (meth) abuse is a growing problem in the United States and worldwide. Cognitive deficits have been observed in meth users, and these deficits are greater after extended meth use (Dean et al, 2013; Marshall and O'Dell, 2012). In human studies,...