Recently, it has been shown that mGluRs, including mGlu3R, mGlu7R, and mGlu8R, are capable of Glu-evoked desensitization and internalization (endocytosis) by GPCR kinases (GRKs) and β-arrestins (β-arrs, consisting of β-arr1 and β-arr2) [48,49,50]. Additionally, by interacting ...