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Group I mGlu receptors are generally coupled to Gq stimulation of phospholipase C and the release of intracellular calcium. The physiologic effects of group I mGlu receptors in the brain are diverse and highlight the importance of these receptors in normal brain function. This chapter describes ...
The structures provide molecular details of the inter- and intra-subunit conformational changes that are required for receptor activation, which distinguish class C G-protein-coupled receptors from those in classes A and B. Furthermore, our structure and functional studies of the mGlu2–mGlu7 ...
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ADM-A阻旋式堵煤開關通用型兩線常開LJ0M-?2415GK抖輪機接近開關SN1-P604LA接近開關E2E-C04S12-WC-C2 2M接近開關 3060204004接近開關SMWHF-D6G接近開關DW-AV-713-M5-276接近開關E2E-X2MC18 2M OMS臨嘉接近開關傳感器WS-J3045T-2臨嘉接近開關傳感器 ...
A simplified mGlu receptor dimer activation model and its domains: VFD - Venus Flytrap Domain; CRD - cysteine-rich domain; 7TMD - transmembrane heptahelical domain, shown as a cylinder with three highlighted transmembrane helices (TM 4–6) within the lipid bilayer and the intracellular C-terminus...
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MGL-3196_CAS号920509-32-6说明书_AbMole中国 分子量435.22 溶解性（25°C）DMSO 分子式C H Cl N O Water <1 mg/mL CAS号920509-32-6Ethanol <1 mg/mL 储存条件3年 -20°C 粉末状 生物活性 MGL-3196 is a liver-targeted selective agonist for the thyroid hormone receptor-β (THR-β) ...
Antibodies have enormous therapeutic and biotechnology potential. G protein-coupled receptors (GPCRs), the main targets in drug development, are of major interest in antibody development programs. Metabotropic glutamate receptors are dimeric GPCRs that c