It is also used off-label in the treatment of Crohn's disease, as a prophylactic agent after surgery5, and in the treatment of Helicobacter pylori infection.7 It has also been studied in the prevention of preterm births and to treat periodontal disease.1,12 Reduce drug development failure ra...
When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treat...
Fixeddrug eruption due to metronidazole: review of literature and a case report. International Journal of Pharma Sciences and Research (IJPSR); March 2012; 3(3): 331-334.Wahlang JB, Sangma KA, Marak MD, Brahma DK, Lynrah KG, Ksih A. Fixed drug eruption due to ...
Do not administer metronidazole to patients who have taken disulfiram within the last two weeks (see PRECAUTIONS, Drug Interactions). Interaction with Alcohol Use of oral metronidazole is associated with a disulfiram-like reaction to alcohol, including abdominal cramps, nausea, vomiting, headaches, and...
of an electron to the nitro group of the metronidazole, and formation of a short-lived nitroso free radical. Because of this alteration of the metronidazole molecule, a concentration gradient is created and maintained which promotes the drug’s intracellular transport. The reduced form of ...
Metronidazole is an antibiotic, amebicide, and antiprotozoal.[1] It is the drug of choice for first episodes of mild-to-moderate Clostridium difficile infection [2]. Metronidazole, taken up by diffusion, is selectively absorbed by anaerobic bacteria and sensitive protozoa. Once taken up by ...
Metronidazole has been reported to potentiate theanticoagulanteffect of warfarin and other oral coumarin anticoagulants, resulting in a prolongation ofprothrombin time. This possible drug interaction should be considered when Metronidazole Injection, USP RTU is prescribed for patients on this type of anticoa...
The precise mechanism of action of metronidazole is unclear. Drug Resistance A potential for development of resistance exists against metronidazole. Resistance may be due to multiple mechanisms that include decreased uptake of the drug, altered reduction efficiency, overexpression of the efflux pumps,...
Instruct patient to be alert for skin rash, blisters, fever or other signs and symptoms of these hypersensitivity reactions; advise patients to stop therapy immediately if they develop any type of rash and seek medical attention Drug interaction overview ...
Type Organic Chemicals Pharmaceutical Technology Chemical Synthesis Drug Reg./Approval No. H13022487 Production Line GMP Approved Transport Package 80 Bags/Carton Specification 100ML Trademark SHIMEN Origin China HS Code 3004909099 Product Description Metronidazole Injection Name: Metronidazole...