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Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.2,9 The possibility of the generation of these formulations comes from the lower systemic bioavailability of the...
A review of the biological activities, pharmacokinetic properties and clinical effectiveness of metoprolol tartrate, a new beta-adrenoceptor which preferentially antogonizes the action of sympathomimetic amines on Bl-receptors, blocking ... Koch-Weser,Jan - 《New England Journal of Medicine》 ...
Methods to compare dissolution profiles and a rationale for wide dissolution specifications for metoprolol tartrate tablets The objectives of this work were to apply several profile comparison approaches to dissolution data of four different but bioequivalent metoprolol tartrate... JE Polli,GS Rekhi,LL ...
Define Metoprolol succinate. Metoprolol succinate synonyms, Metoprolol succinate pronunciation, Metoprolol succinate translation, English dictionary definition of Metoprolol succinate. A trademark for the tartrate salt of the drug metoprolol. American He
The heart rate reduction for 100 mg metoprolol tartrate/day in COMET was only 11.7 beats per minute (bpm) compared to the 15 bpm observed in MDC, on which the dose was based, and 14 bpm in MERIT-HF. It has been suggested that metoprolol tartrate should have been titrated to a higher ...
13.The Cure Hypertension and Chronic Beautiful Tuoluoer Cardiac Failure Curative Effect Is Observed美托洛尔治疗高血压并慢性心力衰竭疗效观察 14.Determination of Metoprolol tartrate sustained-release matrix tablets by HPLCHPLC法测定酒石酸美托洛尔骨架缓释片的含量 ...
2.Capillary electrophoresis determination of metoprolol tartrate tabCapillary electrophoresis determination of metoprolol tartrate tablets;毛细管电泳法测定酒石酸美托洛尔片的含量 英文短句/例句 1.Determination the Content and Related Substances of Metoprolol Tartrate Tablets by HPLCHPLC法测定酒石酸美托洛尔片的含...
Effect on the nasal bioavailability of co-processing drug and bioadhesive carrier via spray-drying with metoprolol tartrate (used as model molecule) in order to develop a powder suitable for nasal drug delivery via a one-step manufacturing process. The... D Coucke,C Vervaet,P Foreman,... - ...