Pharmacological action No Actions Binder General Function Toxic substance binding Specific Function Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the ...
Pharmacological action Nifedipine is a dihydropyridine calcium channel blocker. Its main uses are as an antianginal(抗心绞 痛药)and antihypertensive. It is used to treat coronary artery spasm (CAS, 冠 状动脉痉挛), myocardial infarction (MI心肌梗塞) although a large number of other uses ...
. Metoprolol CR/XL utilises the succinate salt of the drug which is less water soluble than the tartarate salt. Each metoprolol CR/XL tablet comprises individual spherical pellets of the active drug coated with a non-proteolytic polymeric membrane (mainly ethylcellulose) compressed together with ta...
8.0 Pharmacological action Metoprolo has selective blocking effect on beta 1 receptor, and has no partial activity and no function of membrane stability. It can significantly reduce the blood pressure of the people with hypertension, and do not cause erect hypotension and electrolyte disorder. It ...
IJzerman, in Trends in Pharmacological Sciences, 2006 A study using isolated cardiac myocytes taken from failing human hearts examined the ligand properties of three β-blockers used in clinical trials. The study revealed that two of these compounds, metoprolol and carvedilol, had inverse agonist ...
that displayed antitumor and antiviral activities, and concluded: “The incorporation of heterocyclic motifs into triterpenes sometimes brings a new mechanism of action, increased activity and better pharmacological properties, which makes the area of heterocyclic triterpenes a hot topic in the chemistry of...
According to the MERIT-HF15,24and RESOLVD studies24, metoprolol succinate, a cardioselective β-blocker, is one of the β-blockers recommended for preventing the incidence of death in HF patients2. Additionally, CHF patients reported improvement in QoL in terms of physical activity, social funct...
Pharmacological action Metoprolo has selective blocking effect on beta 1 receptor, and has no partial activity and no function of membrane stability. It can significantly reduce the blood pressure of the people with hypertension, and do not cause erect hypotension and electrolyte disorder. It can ...