There were eleven visits in seven patients in which the subject had a HR less than 50 bpm; five visits in three patients in which subjects reported lightheadedness; six visits in six patients with abdominal pain, nausea, or vomiting, and one in which a subject reported sexual disturbance....
This medicine may cause some people to become less alert than they are normally. if this side effect occurs, do not drive, use machines, or do anything else that could be dangerous if you are not alert while using metoprolol injection. ...
While less common, the most serious side effects of metoprolol are described below, along with what to do if they happen. Heart Rate Changes.Metoprolol can make your heart beat slower than normal(bradycardia). Call your healthcare provider right away if you ...
While less common, the most serious side effects of metoprolol are described below, along with what to do if they happen. Heart Rate Changes. Metoprolol can make your heart beat slower than normal (bradycardia). Call your healthcare provider right away if you have any of the following symptom...
Heart rate slowing, depression, diarrhea, skin rash, and shortness of breath are the most common side effects of metoprolol. Side effects are similar for both metoprolol tartrate and metoprolol succinate because they both contain the same active drug, metoprolol. Dry eyes, blurred vision, ...
Significant beta-blocking effect (as measured by reduction of exercise heart rate) occurs within 1 hour after oral administration, and its duration is dose-related. For example, a 50% reduction of the maximum effect after single oral doses of 20, 50, and 100 mg occurred at 3.3, 5.0, and...
Evidence of the 'cardioselective' properties of metoprolol is provided by the finding that metoprolol inhibits the heart rate response to isoprenaline at doses about one-fifteenth of those required to inhibit the vasodilator response. However, there is experimental evidence that metoprolol is somewhat ...
contrast, the DPWG have issued guidance stating that inCYP2D6IMs and PMs, where a gradual reduction in heart rate is desired or in the event of symptomatic bradycardia, doses of metoprolol should be increased in smaller steps and/or no more than 25% (in PMs) or 50% (in IMs) of the ...
associated with bradycardia (slow heart rate),hypotension,stroke, and death. However, long-term therapy with metoprolol should not be routinely withdrawn before major surgery. The impaired ability of the heart to respond to reflex adrenergic stimuli may increase the risks of general anesthesia and ...
Monitor heart rate, BP, and ECG during IV therapy.Discontinue therapy in patients with severe intolerance to IV therapy.Rate of AdministrationAdminister as a rapid IV injection.DosageAvailable as metoprolol tartrate and metoprolol succinate; dosage expressed in terms of the tartrate....