otherantihypertensivedrugsofadifferentclass.MYKROXTablets,amorerapidlyavailableformof metolazone,areintendedforthetreatmentofnewpatientswithmildtomoderatehypertension.Adosetitration isnecessaryifMYKROXTabletsaretobesubstitutedformetolazonetablets,USP,inthetreatmentof hypertension.SeepackagecircularforMYKROXTablets. UsageIn...
Find information on Metolazone in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.
Find information on Metolazone in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.
Monitor BP regularly (i.e., monthly) during therapy and adjust dosage of the antihypertensive drug until BP controlled. If unacceptable adverse effects occur, discontinue drug and initiate another antihypertensive agent from a different pharmacologic class. Assess patient's renal function and ...
ZAROXOLYNisalsoindicatedforthetreatmentof hypertension,aloneorincombinationwithother antihypertensivedrugsofadifferentclass. CENTERFORDRUGEVALUATIONANDRESEARCH 017386Orig1s040 CONTENTS Reviews/InformationIncludedinthisNDAReview. ApprovalLetterX OtherActionLetters ...
As most of the drug is excreted by the renal route, accumulation may be observed. Orthostatic hypotension has been observed in some patients. Hypercalcemia may infrequently occur with metolazone therapy, especially in patients taking high doses of vitamin D or with high bone turnover states, and...
and nonthiazide diuretics. When symptoms consistent with severe electrolyte imbalance appear rapidly, drug should be discontinued and supportive measures should be initiated immediately. Parenteral electrolytes may be required. Appropriateness of therapy with this class of drugs should be carefully re...
2006,Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions (Fifteenth Edition) Explore book Organs and Systems Electrolyte balance Metolazonecauses a greater degree of potassium depletion thanthiazides(SED-11, 424). In order to avoid seriouselectrolyte...
Find information on Metolazone in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Davis Drug Guide PDF.
The incidence of drug-induced liver injury with rosiglitazone has been calculated at 0.02% for alanine aminotransferase activity 10 times the upper end of the reference range and 0.001% for jaundice [170]. The above case report is unusual because, although liver damage is rare, hepatic necrosis ...