N6-methyladenosine (m6A) modification of mRNA, mediated by methyltransferase-like 3 (METTL3), is one of the well-identified mRNA modifiers associated with the pathogenesis of AML. High level ofMETTL3mRNA is detected in AML cells, thus can be a potential target therapy for AML. This is a ...
Methyltransferase-like protein 21C (METTL21C) is a PKMT implicated in muscle biology that has been reported to methylate valosin-containing protein/p97 (VCP) and heat shock 70-kDa protein 8 (HSPA8). However, a clear in vitro methyltransferase activity for METTL21C remains yet to be ...
Here, we identify methyltransferase-like 21e (Mettl21e), a member of newly classified nonhistone methyltransferases, as a gene enriched in type IIb myofibers. The expression of KD myotubes. These results demonstrate that Mettl21e functions to maintain myofiber size through inhibiting proteasome-...
which has been demonstrated to serve oncogenic roles in various types of cancer; however, the exact function of METTL3 in oesophageal squamous cell carcinoma (ESCC) has not been determined. The
Human Probable methyltransferase-like protein 15 (METTL15) ELISA Kit检测范围:0.156 ng/ml - 10 ng/ml保存建议 4℃下运输。收到该Human Probable methyltransferase-like protein 15 (METTL15) ELISA Kit产品后,按照试剂盒手册中的储存说明储存试剂盒。其他...
Recombinant Human METTL1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 296 amino acids(1-276a.a.) and having a molecular mass of 33.6kDa. METTL1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary
Anti-METTL3 antibody (ab195352, 1:1000 dilution) and anti-HIF-1α (ab1, 1:500 dilution) were from Abcam (Cambridge, UK). 2.8. Cell Proliferation Assay and Cell Migration Assay The cell proliferation experiment was carried out using the cell counting kit-8 (CCK8). In a 96-well plate...
中文名称:Recombinant Methyltransferase Like Protein 21C (METTL21C) 中文同义词: 甲基转移酶样蛋白21C(METTL21C)重组蛋白 英文名称:Recombinant Methyltransferase Like Protein 21C (METTL21C) 英文同义词: Recombinant Methyltransferase Like Protein 21C (METTL21C) CAS号: 分子式: 分子量:0 EINECS号: Mol文件:...
为探讨鸡甲基转移酶样蛋白5(Methyltransferase like protein 5,METTL5)基因的序列和结构,采用RT-PCR方法克隆该基因,并用生物信息学方法分析该基因的特征;利用定量PCR(qPCR)方法检测METTL5基因的组织表达模式和母鸡叶酸缺乏对仔鸡腹脂中该基因表达的影响。结果表明,鸡METTL5基因的cDNA序列长度为702 bp(Genbank accession...
METTL7Bm6A modificationACSL3FerroptosisBladder cancer (BC) is a malignant tumor. Methyltransferase-like 7B (MEETL7B) is a methyltransferase and its role in BC has not yet been revealed.#Stable METTL7B knockdown or overexpression were achieved by lentiviral transduction in SW780 and TCCSUP cell ...