Important drug or substance interactions/effects with methylprednisolone Medicinal product class or type Interaction/Effect - MEDICINAL PRODUCT or SUBSTANCE Antibacterial CYP3A4 INHIBITOR. In addition, there is a potential effect of - ISONIAZID methylprednisolone increasing the acetylation rate and clearance ...
Important drug or substance interactions/effects with methylprednisolone Medicinal Product Class or Type - MEDICINAL PRODUCT or SUBSTANCE Antibacterial - ISONIAZID Antibiotic, Antitubercular - RIFAMPIN Anticoagulants (oral) Anticonvulsants - CARBAMAZEPINE Anticonvulsants - PHENOBARBITAL - PHENYTOIN Anticholinergics...
Mechanism of action Methylprednisolone is an analog of prednisolone that exhibits a more prolonged effect than prednisolone and cortisone; it has practically no mineralocorticosteroid activity and is better tolerated. Clinical Use Adding a 6α-methyl group to prednisolone increases the glucocorticoid activi...
ClassAnti-inflammatories; Antiasthmatics; Corticosteroids Mechanism of ActionImmunosuppressants; Steroid receptor agonists Orphan Drug Status Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases. ...
Mechanism of Action Potent glucocorticoid with minimal to no mineralocorticoid activity Modulates carbohydrate, protein, and lipid metabolism and maintenance of fluid and electrolyte homeostasis Controls or prevents inflammation by controlling rate of protein synthesis, suppressing migration of polymorphonuclear le...
[5]. Glucocorticoids are an extremely important class of regulatory molecules in the body, which is central to regulating the development, growth, metabolism and immune function of the body. It is the most important regulatory hormone of the body’s stress response, as well as the most widely...