Objective. The objective of this study was to evaluate differences in the pharmacodynamic (PD) profile of 2 second-generation extended-release (ER) formulations of methylphenidate (MPH): Metadate CD (MCD; methylphenidate HCl, US Pharmacopeia) extended-release capsules, ...
SummaryObjective:The objective of the study was to investigate the effectiveness and safety of Metadate庐 CD (methylphenidate HCl, USP) Extended Release Ca... S. J. Hirshey Dirksen,J. M. D'Imperio,D. Birdsall,... - 《Health Pac Bulletin》 被引量: 20发表: 2008年 Methylphenidate (generic...
9,33 The formulation of methylphenidate varied between the RCTs, including immediate release (Ritalin [Novartis Pharmaceutical Corp]; Equasym [Shire PLC]), extended release (Metadate CD [UCB Inc]; Ritalin LA [Novartis Pharmaceutical Corp]), OROS (Concerta [Actavis]), and methylphenidate ...
Children (184: 48 females; mean [SD]; age, 9.58 [1.83]; years) entered a double-blind, crossover trial of Concerta, MetadateCD/Equasym XL, or placebo. Attention-deficit/hyperactivity disorder symptoms were recorded at seven time points across the school day on the seventh day of treatment...
(methylphenidateHCL)Sustained-ReleaseTablets3/30/1982–21-121Concerta(methylphenidateHCL)Extended-ReleaseTablets8/11/200021-259MetadateCD(methylphenidateHCL)Extended-ReleaseCapsules4/3/2001–21-284RitalinLA(methylphenidateHCL)Extended-ReleaseCapsules6/5/2002–21-802FocalinXR(dex-methylphenidate)ExtendedRelease...