Peak concentration and AUC were about 26 and 6% higher, respectively, for Cotempla XR-ODT (single dose of two 25.9-mg extended-release orally disintegrating tablets [equivalent to 60 mg of methylphenidate hydrochloride]) than for a 60-mg extended-release capsule formulation of methylphenidate ...
If you cannot swallow an extended-release capsule whole, open it and mix the medicine with soft food such as applesauce, pudding or yogurt. Swallow the mixture right away without chewing.You must chew the chewable tablet before you swallow it....