VITAMIN B complexBackground: B vitamins such as folate (B9), B6, and B12 are key in one carbon metabolism, which generates methyl donors for DNA methylation. Several studies have linked differential methylation to self-reported intakes of folate and B12, but these estimates can be imprecise, ...
Understanding Folate (Methylfolate) The other most important vitamin B is folate which plays a significant role in DNA synthesis, cell division and red blood cell formation. The body can use methylfolate which is the active form of folate. This is greatly important in people having specific gene ...
The self-reported intake of folate and vitamin B6 had consistent but non-significant associations with the epigenetic signals. Conclusion Metabolomic biomarkers are a valuable approach to investigate the effects of dietary B vitamin intake on the human epigenome....
19. Process for the production of a complex according to claim 1, wherein a) the methylated derivative of β-cyclodextrin and the vitamin D compound are added together in soluble form, b) are stirred for 1-24 hours, c) the optionally obtained solid is filtered off and optionally dried, ...
phosphorylated MeCP2 can bind to DGCR8 and interfere with the assembly of the DROSHA/DGCR8 complex to inhibit processing of primary transcripts to precursor miRNAs46,47. Yet, whether this mechanism of MeCP2-DGCR8 interaction underlies all cases of MeCP2 negative regulation of miRNA processing is...
Preeclampsia (PE) is a complex pregnancy disorder. It is not extensively known how the metabolic alterations of PE women contribute to the metabolism of newborn. We applied liquid chromatography-mass spectrometry (LC-MS) based non-targeted metabolomics t
The invention relates to complexes consisting of vitamin D compounds or analogues thereof having a 5Z,7E,10(19)-triene system and methylated derivatives of ß-cyclodextrin, in particular a complex made of (thiazol-2-yl)-26,27-dinor-9,10-secocholesta-5,7, 10(19)-triene-1,3,25-triol ...
The invention relates to complexes that consist of vitamin D compounds or analogs thereof with a 5Z,7E,10(19)-triene system and methylated derivatives of β-cyclodextrin, in particular a complex that consists of (thiazol-2-yl)-26,27-dinor-9,10-secocholesta-5,7,10(19)-triene-1,3,25-...
Y. Sueishi, M. Hori, N. Inazumi, Characterization of inclusion complex of vitamin E compound with 2,6-di-O-methylated b-cyclodextrin as the solubility enhancer and its kinetic determination for radical scavenging ability, J. Incl. Phenom. Macrocycl. Chem. 72 (2012) 467-472....
COMPLEXBINDINGLumazine synthase and riboflavin synthase catalyze the last two steps in the biosynthesis of riboflavin, a vitamin that is involved in many critical biochemical reactions that are essential for the maintenance of life. To obtain inhibitors and structural probes that could be useful in ...