1-Pyrazolo[4,3-]pyrimidines were previously disclosed as a potent second generation class of phosphodiesterase 5 (PDE5) inhibitors. This work explores the ... MB Tollefson,BA Acker,EJ Jacobsen,... - 《Bioorganic & Medicinal Chemistry Letters》 被引量: 36发表: 2010年 5-[(2-Bromophenylami...
treatment of CNS disease comprising a phenoxy methyl compound that inhibits at least one phosphodiesterase 10, for example, 4-(4-(Imidazo [1, 2-b] pyridazine-2-ylmethoxy) phenyl)-5-(4-methoxyphenyl)-2, 2 dimethylfuran-3(2H)-one methanesulfonate, and pharmacologically acceptable carrier or ...
PF-04217903 methanesulfonatec-Met抑制剂956906-93-7 PF-04447943PDE9抑制剂1082744-20-4 PF-04457845有效的FAAH选择性抑制剂1020315-31-4 PF-04971729SGLT inhibitor1210344-57-2 PF-3758309PAK4抑制剂898044-15-0 PF-543SphK1选择性抑制剂1415562-82-1 ...
treatment of CNS disease comprising a phenoxy methyl compound that inhibits at least one phosphodiesterase 10, for example, 4-(4-(Imidazo [1, 2-b] pyridazine-2-ylmethoxy) phenyl)-5-(4-methoxyphenyl)-2, 2 dimethylfuran-3(2H)-one methanesulfonate, and pharmacologically acceptable carrier or ...