Here we shall summarize some of the definitions and concepts characterizing genetic sequences [18, 47] and outline the basic problems of their study in the context of the theory of molecular evolution.These keywords were added by machine and not by the authors. This process is experimental and...
All processes that occur within living organisms are intimately linked to biological macromolecules such as proteins, nucleic acids, or polysaccharides. Phospholipid membranes compartmentalize the interior of the cell and separate "inside" from "outside". Elucidating the structures of all these biomolecular...
X-ray crystallography at X-ray free-electron laser sources is a powerful method for studying macromolecules at biologically relevant temperatures. Moreover, when combined with complementary techniques like X-ray emission spectroscopy, both global structures and chemical properties of metalloenzymes can be...
2002b. Ab initio QM/MM and free energy calculations of enzyme reactions. In Computational methods for macromolecules: Challenges and applications (eds. T. Schlick and H.H. Gan), pp. 332-354. Springer-Verlag, New York... Y Zhang,H Liu,W Yang 被引量: 28发表: 2002年 加载更多研究...
A blind benchmark of analysis tools to infer kinetic rate constants from single-molecule FRET trajectories Article Open access 14 September 2022 Main FRET1, also known as fluorescence resonance energy transfer, is a well-established method for studying biomolecular conformations and dynamics at both ...
The function of bio-macromolecules is determined by both their 3D structure and conformational dynamics. These molecules are inherently flexible systems di... PRL Markwick,T Malliavin,M Nilges,... - 《Plos Computational Biology》 被引量: 118发表: 2008年 Computational Approaches for Studying the Gr...
C. Fredriksson et al., “The Piezoelectric Quartz Crystal Mass and Dissipation Sensor: A Means of Studying Cell Adhesion,” Langmuir, vol. 14, 1998, pp. 248-251. J. Fritz et al., “Force-mediated kinetics of single P-selectin/ligand complexes observed by atomic force microscopy,” Proc...
Pitts, J. D., and Simms, J. W., 1977, Permeability of junctions between animal cells: Intercellular transfer of nucleotides but not of macromolecules,Exp. Cell Res.104:153–163. ArticlePubMedCASGoogle Scholar Politoff, A. L., Socolar, S. J., and Loewenstein, W. R., 1969, Permeabilit...
(1-D grid) structure that can represent molecular sequences such as DNA, macromolecules/polymers, protein sequences also130,131. In addition to the chemical constituents as in the chemical formula, bondings (such as double and triple bondings) are represented by special symbols (such as ’=...
Molecular recognition, which is the process of biological macromolecules interacting with each other or various small molecules with a high specificity and... D Xing,L Yi,YL Xia,... - 《International Journal of Molecular Sciences》 被引量: 60发表: 2016年 Fluorescence polarization/anisotropy approac...