The alkyne-dicobalthexacarbonyl complexes can be also prepared in situ by the reduction of cobalt bromide with sodium naphthalene under CO atmosphere followed by CuBr treatment in the presence of alkynes. The complexes prepared in this way also give cyclopentenones on heating with norbornene, but ...
Step-by-Step Solution1. Preparation of Alkanes: a. Hydrogenation of Unsaturated Hydrocarbons: - Alkenes and alkynes can be converted into alkanes through hydrogenation. - For exa
An Ir-Pt Catalyst for the Multistep Preparation of Functionalized Indoles from the Reaction of Amino Alcohols and Alkynyl Alcohols The 1,2,4-trimethyltriazolylidene (ditz) ligand allows the preparation of homo- and heterodimetallic complexes of Pt2 and Ir–Pt. These two complexes have ......
B. A stepwise Huisgen cycloaddition process: copper (I)-catalyzed regioselective “ligation” of azides and terminal alkynes. Angew. Chem. Int. Ed. 114, 2708–2711 (2002). Article ADS Google Scholar Fantoni, N. Z., El-Sagheer, A. H. & Brown, T. A hitchhiker’s guide to click-...
The amide bond is an important linkage ubiquitous in nature and technology found in many small molecules and materials. Formation of amide bonds is most easily accomplished via condensation at high temperatures using amines and carboxylic acids, but pept
期刊名称:《Synthesis: International Journal of Methods in Synthetic Organic Chemistry》 | 2016年第19期 关键词: allenes; asymmetric synthesis; diastereoselectivity; silylzincation; zincates; 9.Preparation of Morpholines and Benzoxazines Starting from Nitroepoxides 机译:从硝基环氧化合物制备吗啉和苯并...
Controlled trifluoromethylation reactions of alkynes through visible-light photoredox catalysis. Angew. Chem. Int. Ed. 53, 539–542 (2014). Google Scholar Merino, E. & Nevado, C. Addition of CF3 across unsaturated moieties: a powerful functionalization tool. Chem. Soc. Rev. 43, 6598–6608 ...
Novel crystalline polymorphic forms, Forms A, B, C, D, and E of a compound of Formula I, which has been found to be a potent inhibitor of LFA-1, are disclosed. Methods of preparation and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed in this invention.Inve...
Scheme I refers to the preparation of tetracycline compounds which may be prepared from a starting compound of formula 1, a clinically useful tetracycline antibiotic named doxycycline. It has been found that 6-(substituted)-5-hydroxy-6-deoxytetracyclines (1, R2=CH3, doxycycline) or their mineral...
Chou et al., “Sterospecific Synthesis of 2-Deoxy-2, 2-difluororibonolactone and its Use in the Preparation of 2′-Deoxy-2′, 2′-difluoro-B—D-ribofuranosyl Pyrimidine Nucleosides: The Key Role of Selective Crystallization,” Synthesis, 565-570, 1992. Chow and Erdtman, “The chemistry...