Spatial proteomics technologies such as immunofluorescence have been around longer than other spatial biology methods, such as spatially resolved transcriptomics, which was our Method of the Year in 2021, so why are we choosing it as Method of the Year now? For one, we were excited by the rece...
Nat. Methods https://doi.org/10.1038/s41592-024-02546-6 (2024). Article PubMed Google Scholar Download references Rights and permissions Reprints and permissions About this article Cite this article Method of the Year 2024: spatial proteomics. Nat Methods 21, 2195–2196 (2024). https://doi...
Inc. (Nasdaq: AKYA) (“Akoya”), The Spatial Biology Company®, announced thatNature Methods, one of the world’s leading scientific journals, has selected spatial proteomics as its prestigious“Method of the Year 2024”, recognizing the transformative potential of this approach in advancing biol...
Spatially resolved transcriptomics provides the opportunity to investigate the gene expression profiles and the spatial context of cells in naive state, but at low transcript detection sensitivity or with limited gene throughput. Comprehensive annotating of cell types in spatially resolved transcriptomics to ...
University of SouthamptonAdam Prügel-BennettUniversity of SouthamptonMahesan NiranjanUniversity of SouthamptonSpringer, ChamSquires S, Ewing R, Prugel-Bennett A, et al (2017). A method of integrating spatial proteomics and protein-protein interaction network data. International Conference on Neural ...
Development of a Sensitive, Scalable Method for Spatial, Cell-Type-Resolved Proteomics of the Human Brain. Development of a Sensitive, Scalable Method for Spatial, Cell-Type-Resolved Proteomics of the Human Braindoi:10.1021/acs.jproteome.8b00981... Simon,Davis,Connor,... - 《Journal of ...
While nearly comprehensive proteome coverage can be achieved from bulk tissue or cultured cells, the data usually lacks spatial resolution. As a result, tissue based proteomics averages protein abundance across multiple cell types and/or localizations. With proteomics platforms lacking sensitivity and ...
解读人:李思奇,Development of a sensitive, scalable method for spatial, cell-type-resolved proteomics of the human brain. (一种用于研究人类大脑基于空间或细胞类型的蛋白质组学的灵敏方法) 发表时间:(2019年4月) 一、概述: 本文报道了一种可研究人类大脑组织中特定神经细胞的蛋白质组学的方法。作者通过激光...
- 《Proteomics》 被引量: 3发表: 2015年 Indirect 2D Touch Panning: How Does It Affect Spatial Memory and Navigation Performance? We present experimental work which explores the effect of touch indirectness on spatial memory and navigation performance in a 2D panning task. In this reg... H ...
Robotically assisted proteomics provides insights into the regulation of multiple proteins achieving excellent spatial resolution. However, developing an effective method for spatially resolved quantitative proteomics of formalin fixed paraffin embedded tissue (FFPE) in an accessible and economical manner remains...