The invention relates to a method for preparing liposomes, which consists in forming, in a first step, a W/O type emulsion by dispersion of a first aqueous phase in a water-immiscible organic solvent in the presence of molecules composed of a lipophilic fraction and a hydrophilic fraction, ...
A simple method for the preparation of liposomes for pharmaceutical application and character- ization of liposomes. J Pharm Pharmacol. 1991;43:154Y161.Perrett S, Golding M, Williams WP,et al.A simple method for the preparation of liposomes for pharmaceutical application: characterization of the ...
OF THE DISCLOSURE A method for producing liposomes which comprises mixing liposome membrane components with a water-soluble non-volatile solvent and, then, dispersing the mixture in an aqueous medium. The pharmaceutically acceptable liposome preparation as a drug delivery system can thus be produced ...
L. Mallett, " Targeted Liposomes: A Method For Preparation and Analysis ", Analytical Biochemistry III, pp. 54-59, 1981.V. K. Jansons and P. L. Mallett, "Targeted Liposomes: A Method For Preparation And Analysis, Analytical Biochemistry III, pp. 54-59, 1981....
Heparin-based preparations wherein heparin is retained in or on liposomes. The lipids of said liposomes are preferably phospholipids comprising acyl chains derived from non saturated fatty acids, advantageously essential acids. These heparin-liposomes preparations have heparinic activity when administered in...
摘要: A method of producing liposomal products which comprises treating a positively or negatively charged, freeze- or spray-dried liposomal preparation with an aqueous solution of a drug charged oppositely to the charge of the liposomes.收藏 引用 批量引用 报错 分享 文库来源 其他来源 求助全文 ...
方法:采用pH 梯度法制备澳洲茄边碱脂质体,以包封率为指标进行工艺优化,通过SephadexG-50 葡聚糖凝胶柱分离脂质体,高效液相色谱法测定澳洲茄边碱的包封率。结果:制备澳洲茄边碱脂质体的最佳条件,药物与卵磷脂的质量比为1颐30,胆固醇与卵磷脂质量比为1颐4,脂质体外水相pH 值最终调至6.5,孵育温度为55益,此时的包...
Polyclonal anti-CRP was introduced onto liposomes containing Ru(bpy)32+ (2,2′-bipyridine) and prepared as an ECL tag for a sandwich type immunoassay of CRP, showing a detection limit of 100 ng/mL for human CRP with good linearity of ECL intensity versus antigen concentration over the range...
The present invention provides a liposome having co-encapsulated in its intraliposomal aqueous core at least two amphipathic drugs, the liposomes being characterized by one of the following: the amphipathic drugs are co-encapsulated at a pre-determined ratio; the liposome comprises one or a combinati...
Problem to be solved: to provide a method for producing liposomes using poorly soluble substances as raw material of the main component in a fluid substanc... 井關 貴博 被引量: 0发表: 2020年 Method for producing liposome preparation An object of the present invention is to provide a method...