Scope: Inadequate intake of choline commonly leads to liver diseases. Methionine- and choline-deficient diets (MCDD) induce fatty liver in mice which is partly mediated by triglyceride (TG) lipolysis in white adipose tissues (WATs). Because Fatp4 knockdown has been shown to increase adipocyte ...
methionine-choline-deficient diet 蛋氨酸胆碱缺乏饮食 --- 如有疑问欢迎追问!满意请点击右上方【选为满意回答】按钮
3.5.2.1Methionine- and Choline-Deficient Diet MCDdiet is a classical dietary model of NASH. Although the diet comprises highsucrose(40%) and fat (10%), it lacksmethionineandcholine, which are indispensable for hepatic mitochondrial β-oxidation and very low-density lipoprotein (VLDL) synthesis (...
Melatonin is not only a powerful antioxidant but also an anti-inflammatory and anti-apoptotic agent. We aimed to evaluate the effects of melatonin on methionine- and choline-deficient diet (MCDD)-induced NASH in rats. Thirty-two male Wistar rats were divided into four groups. Two groups were...
蛋氨酸缺乏饲料(Methionine Deficient Diet) 蛋氨酸(methionine,Met)也称甲硫氨酸,不仅是蛋白质合成的必需营养素,而且作为硫的供体,在体内发挥关键作用,并且与高同型半胱氨酸血症、甲基化和脂肪代谢有关,另外也有癌症、衰老相关的报导用到。蛋氨酸缺乏饲料正是用于研究蛋氨酸缺乏情况下机体功能改变的饲料。
Lipogenic diets that are completely devoid of methionine and choline (MCD) induce hepatic steatosis. MCD feeding also provokes systemic weight loss, for unclear reasons. In this study, we found that MCD feeding causes profound hepatic suppression of the gene encoding stearoyl-coenzyme A desaturase-1...
美[mə'θaɪəˌnin] 英[me'θaɪəni:n] n.【生化】蛋氨酸 网络甲硫胺酸;甲硫氨酸;蛋胺酸 英汉 英英 网络释义 n. 1. 【生化】蛋氨酸,甲硫氨酸
英文名称:Methionine/Choline Deficient Diet 别名:MCD饲料 Harlan Teklad动物饲料 Harlan代理 欢迎新老客户访问Harlan官网或者咨询中国代理商上海金畔生物获取更多详细资料。 Amino acid defined | Envigo A few amino acid defined formulas are shown below. This type of diet is used when a diet needs to be d...
Background: Methionine-choline-deficient (MCD) diets cause steatohepatitis in rodents and are used to model fatty liver disease in human beings. Recent studies have identified sucrose as a major contributor to MCD-related liver disease through its ability to promote hepatic de novo lipogenesis.Aims:...
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