The distribution of methanol itself, on the other hand, does not change with variations of blood pH.The toxicity of FA is determined essentially by the pH. Hemolytic activity is used as a model of its cytotoxic effect. Hemolysis increases with falling pH, and thus runs parallel to the ...
† Tair Lapidot,MDW‡ And,† Joseph Kanner - 《Journal of Agricultural & Food Chemistry》 被引量: 237发表: 2002年 A new mechanism for the aerobic catabolism of dimethyl sulfide. Aerobic degradation of dimethyl sulfide (DMS), previously described for thiobacilli and hyphomicrobia, involves...
Mechanism of toxicity, clinical course, diagnosis and treatment. Methanol and ethylene glycol poisonings share many characteristics both clinically and biochemically. Both alcohols are metabolised via alcohol dehydrogenase to their toxic metabolites. Methanol is slowly metabolised to formaldehyde whic... D...
of the toxicity of methanol from animal data, potential environmental effects as well as human effects. The animal data, which goes to making up the majority of the data on the toxicity of methanol and the mechanism of action, is reviewed as it relates to the potential toxicity in humans. ...
A compelling explanation of the dose region of adverse effects of the U-shaped curve with high ethanol consumption, which shows increased risk of these same diseases, could be the mechanism by which humans habituate to high consumption of ethanol. The induction of the P450 hepatic microsomal ethan...
Methanol and ethylene glycol poisonings: mechanism of toxicity, clinical course, diagnosis and treatment Med. Toxicol., 1 (1986), pp. 309-334 View in ScopusGoogle Scholar [159] J. Liesivuori, H. Savolainen Methanol and formic acid toxicity: biochemical mechanisms Pharmacol. Toxicol., 69 (1991...
Figure 1 Mechanism of methanol synthesis by CO2 hydrogenation through hydrocarboxyl and formate pathway. 3. Improvement in methanol production by regulating the composition of synthetic gas mixture and raw biogas:Raw biogas can be an alternative feedstock to pure methane (CH4) for methanol production....
Modification of Methanol Potentiation of CC14 Toxicity in Rats by Chloramphenicol and Salicylatedoi:10.3109/01480548209017775ABSTRACT The mechanism by which methanol potentiates CC14 hepatotoxicity was studied in rats. Chloramphenicol, an inhibitor of cytochrome P-450, blocked the increase of serum glutamate...
Besides for the mechanism of electron transfer between PQQ and heme c, QH-ADH type II is also interesting from an applied point of view since it is the primary enzyme converting ethanol into vinegar in Acetic acid bacteria. Moreover, it has the required activity and enantioselectivity for ...
(serum, plasma and urine), cell and tissue culture supernatants, fruit juice and other non-alcoholic beverages and anaerobic microbial cultures.Principle: The Methanol Assay Kit utilizes an enzymatic mechanism by which conversion of methanol is correlated stoichiometrically with generation of a ...