Metformin has been the mainstay of therapy for diabetes mellitus for many years; however, the mechanistic aspects of metformin action remained ill-defined. Recent advances revealed that this drug, in addition to its glucose-lowering action, might be promising for specifically targeting metabolic differ...
Metformin, if not contraindicated, should be considered first line-therapy for the management of type 2 diabetes mellitus. Immediate-release: Take in divided doses 2 to 3 times a day with meals; titrate slowly to minimis gastrointestinal side effects. In general, significant responses are not ...
Cohrane Database of Systematic ReviewsSaenz Calvo A, Fernandez Esteban I, Mataix Sanjuan A, Ausejo Segura M, Roque M, Moher D. [Metformin for type-2 diabetes mellitus. Systematic review and meta-analysis] Aten Primaria 2005; 36(4):183-91. Review. Spanish 13. Peters AL. Using ...
Art and Images in Psychiatry Best of the JAMA Network Caring for the Critically Ill Patient Clinical Crosswords from JAMA Coronavirus Resource Center Evidence-Based Medicine: An Oral History Fishbein Fellowship Genomics and Precision Health Health and the 2024 US Election Hypertension JAMA Forum Archive...
Metformin is an FDA-approved antidiabetic agent that manages high blood sugar levels in type 2 diabetes patients. It reduces glucose absorption from the intestines, lowers liver glucose production, and improves insulin sensitivity. Metformin is recommended with dietary changes and exercise for better re...
- 《Nature Reviews Endocrinology》 被引量: 303发表: 2012年 [Progress in the prevention of type 2 diabetes]. MetforminType 2 diabetes mellitus is a major health problem associated with excess morbidity and mortality.Defects in the action and/or secretion of insulin... G Schernthaner - 《...
Diabetes research needs to prioritize prevention strategies for at-risk individuals. References Roumen, C., Blaak, E. E., & Corpeleijn, E. (2009). Lifestyle intervention for prevention of diabetes: Determinants of success for future implementation. Nutrition Reviews, 67(3), 132–146. https...
Metformin is one of the most commonly prescribed drugs for management of Type 2 diabetes mellitus. It has been in use for almost five decades. Now, pharmacological properties of this agent are being exapted for use in a number of other indications. New facets of its personality are coming up...
Nature Reviews Endocrinology volume 16, page 131 (2020)Cite this article 3599 Accesses 5 Citations 12 Altmetric Metrics details Metformin is commonly prescribed to manage type 2 diabetes mellitus (T2DM), as it decreases plasma concentrations of glucose by inhibiting hepatic glucose production. The ...
Reviews (1746) Uses What is metformin used for? Metformin is used to help lower blood sugar levels in people withtype 2 diabetes. Metformin may also be used for other conditions as determined by your healthcare provider. How does metformin work (mechanism of action)?