While metformin is a prescribed anti-diabetic drug, that does not mean that you shouldn’t take precautions when using it. For one, metformin is known to interfere with the absorption of B12, and a vitamin B12 deficiency can cause a variety of symptoms, such as fatigue, headaches, and depr...
Metformin is a biguanide derivative which is widely prescribed as an oral drug for diabetes mellitus type 2. This old molecule has recently received a new attention because of its therapeutic properties in oncology, that seem to be independent of its action on glycemia homeostasis. The reappraisal...
When prescribed appropriately, metformin causes few adverse effects—the most common is gastrointestinal upset—and, unlike many other anti-diabetic drugs, does not cause hypoglycemia if used alone. Lactic acidosis (a buildup of lactate in the blood) can be a serious concern in overdose and when...
Metformin is now believed to be the most widely prescribed antidiabetic drug in the world; in the United States alone, more than 48 million prescriptions were filled in 2010 for its generic formulations.This text uses material from Wikipedia, licensed under CC BY-SA Phys.org Daily science news...
Your doctor may have you take extravitamin B12while you are taking this medicine. Take only the amount of vitamin B12 that your doctor has prescribed. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dos...
French physician Jean Sterne published the first clinical trial of metformin as a treatment for diabetes. It was introduced to the United Kingdom in 1958, Canada in 1972, and the United States in 1995. Metformin is now believed to be the most widely prescribed antidiabetic drug in the world...
Do not take Synjardy unless it has been prescribed to you by a healthcare provider. Take it as prescribed. Do not share Synjardy with other people, even if they have the same condition as you. It may harm them. Keep Synjardy out of the reach of children. ...
Metformin, a drug prescribed to treat type-2 diabetes, exhibits anti-cancer effects in a portion of patients, but the direct molecular and genetic interactions leading to this pleiotropic effect have not yet been fully explored. To repur... T Hart,S Dider,W Han,... - 《Scientific Reports...
Metformin, the world’s most prescribed anti-diabetic drug, is also effective in preventing type 2 diabetes in people at high risk1,2. More than 60% of this effect is attributable to the ability of metformin to lower body weight in a sustained manner3. The molecular mechanisms by which met...
OBJECTIVE: Of patients who are prescribed metformin, 10-30% have evidence of reduced vitamin B12 absorption. B12-intrinsic factor complex uptake by ileal c... WA Bauman,S Shaw,E Jayatilleke,... - 《Diabetes Care》 被引量: 525发表: 2000年 Rosiglitazone Therapy Improves Insulin Resistance Param...