Metformin-associated vitamin B12 deficiency is a well-established side effect, especially in patients taking higher doses of metformin or who have existing risk factors. Severe deficiency causes a wide range of systemic disorders. Gait instability, which leads to frequent falling, is ...
This patient had multiple risk factors for developing B12 deficiency: vegetarianism, age, diabetes mellitus and Metformin use. This case highlights the potential need to screen for B12 deficiency in at-risk populations.doi:10.1136/jnnp-2016-315106.152Petrova, Daniela...
Our companion article outlines how metformin use can lead to a clinically significant deficiency in vitamin B12, and describes the problems this can cause. In this comment, we outline a project conducted in four primary care practices that aimed to improve metformin-relat...
We report two cases who had symptomatic vitamin B12 deficiency related to metformin use; the mechanisms are discussed. The clinician must be aware of the possibility of metformin-associated B12 deficiency in users who suffer cognitive impairment, peripheral neuropathy, subacute combined degeneration of ...
Is Metformin-Induced vitamin B12 Deficiency responsible for Cognitive decline in type 2 diabetes? Indian J Psychol Med. 2016;38:285–90. Article PubMed PubMed Central Google Scholar Nelson HD, Cantor A, Pappas M, Weeks C. Screening for anxiety in adolescent and adult women: a systematic ...
Metformin: Vitamin B12 deficiency and peripheral neuropathy: case report
Reversible dementia and seizures due to metformin-induced vitamin B12 deficiency. L'Encephale 50: 474-477, No. 4, Aug 2024. Available from: URL: https://dx.doi.org/10.1016/j.encep.2023.11.030 Download references Rights and permissions Reprints and permissions About this article Cite this ...
Metformin and vitamin B12 deficiency Comment on Tidsskr Nor Laegeforen. 2007 Jan 4;127(1):65. JS Scozzari - 《Archives of Internal Medicine》 被引量: 89发表: 2002年 Miglitol, an α-glucosidase inhibitor, prevents the metformin-induced fall in serum folate and vitamin B12 in subjects with ...
Is metformin-induced vitamin B12 deficiency responsible for cognitive decline in type 2 diabetes? Indian J Psychol med. 2016;38:285–90. PubMed PubMed Central Google Scholar Chiti F, Dobson CM. Protein misfolding, functional amyloid, and human disease. Annu rev Biochem. 2006;75:333–66. ...
For one, metformin is known to interfere with the absorption of B12, and a vitamin B12 deficiency can cause a variety of symptoms, such as fatigue, headaches, and depression. Additionally, the deficiency can also increase the risk of anemia. As such, individuals using metformin should regularly...