However, metformin safety in elderly individuals is unknown. The aim of this study was to identify frequency and risk factors of lactic acid (LA) elevation in ambulatory elderly male US veterans with stable diabetic CKD3 treated with metformin. We studied 92 patients with non-diabetic CKD3 (...
ElderlyIpragliflozinMetforminMuscleSGLT2 inhibitorSitagliptinType 2 diabetesVisceral fatIntroductionTo compare the effects of ipragliflozin, a sodium-glucose transporter 2 inhibitor, with those of metformin on visceral fat (as well as muscles and bones) in Japanese elderly patients with type 2 diabetes (...
Role of vildagliptin in managing type 2 diabetes mellitus in the elderly The prevalence of type 2 diabetes (T2DM) increases with age. Older patients have an increased likelihood for T2DM-related morbidity and mortality. The obje... S Halimi,D Raccah,A Schweizer,... - 《Current Medical Resea...
Age 65 or greater— The risk of metformin-associated lactic acidosis increases with the patient’s age because elderly patients have a greater likelihood of having hepatic, renal, or cardiac impairment than younger patients. Assess renal function more frequently in elderly patients. Radiologic studies...
med-30. Pattern of Metformin Use in Hospitalized Elderly Patients: An Alarming Trend?doi:10.1097/00007611-200311001-00199Sundar VenkateshRakesh ShrivastavaSomnit WilsonMaher YounanSouthern Medical Journal
Objective To analyze the clinical effect of insulin aspart 30 combined with metformin in treatment of elderly patients with newly diagnosed type 2 diabetes... Gao Chun-ya - 《Diabetes New World》 被引量: 2发表: 2015年 Use of metformin in patients with sickle cell disease Hydroxyurea (HU) is...
Metformin has beneficial effects on serum lipid profiles in obese and lean patients with NIDDM, and in other patients with concomitant NIDDM, hypertension and/or hyperlipidaemia. In particular, reduced circulating levels of free fatty acids, triglycerides and low density lipoprotein cholesterol, and incr...
women, and pediatric or geriatric patients, metformin usage may not be commonly safe. The primary potential of lactic acidosis production made it unsafe in some circumstances [40]. It is important to understand the benefit-risk balance of metformin treatment when it comes to elderly patients who ...
Comparison of tolbutamide and metformin in elderly diabetic patients. Diabet Med 1990; 7: 510–514. Article CAS PubMed Google Scholar Donnelly LA, Doney AS, Hattersley AT, Morris AD, Pearson ER . The effect of obesity on glycaemic response to metformin or sulphonylureas in Type 2 diabetes...
29 Although there are many retrospective studies that demonstrate an association of prostate cancer with metformin use, Margel and colleagues did not find significant association between metformin use and prostate cancer incidence in elderly patients with diabetes.30...