Metforminis anantidiabetic drugwell-known for its ability to protect against age-related diseases and extend life and health spans inC. elegansand mice models [218,219].Metforminwas the first medicine tested for its anti-aging effects in a largeclinical trial(Targeting Aging by Metformin) [220,...
Metformin (Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet) is a medication prescribed to treat type 2 diabetes and the prevention of type 2 diabetes in patients who are at risk for type 2 diabetes. Side effects of metformin include loss of appetite, bloating, heartburn, gas, nausea, a...
MetPro™ tablets contain Metformin, which works to reduce cholesterol and blood sugar levels for diabetes sufferers and improve the body's use of insulin
Metformin is a well-known anti-diabetic drug that has been repurposed for several emerging applications, including as an anti-cancer agent. It boasts the distinct advantages of an excellent safety and tolerability profile and high cost-effectiveness at less than one US dollar per daily dose. Epid...
More recently, biohackers are tapping into the potential of metformin for its anti-aging properties. Recently, metformin has gained attention in the field of anti-aging research for its ability to modulate numerous aging-related pathways.[3] ...
Kanto K, Ito H, Noso S, Babaya N, Hiromine Y, Taketomo Y et al (2017) Effects of dosage and dosing frequency on the efficacy and safety of high-dose metformin in Japanese patients with Type 2 diabetes mellitus. J Diabetes Investig 9(3):587–593. https://doi.org/10.1111/jdi.12755...
alive mice in both groups were healthy, and there was no significant difference in body weights and organ weights between both groups (Table1). Therefore, these results indicated that the dosage of metformin used in the study was safe for the animals and could be used for subsequent ...
Metformin also reportedly has antiaging (10), antiobesity (11, 12, 13), and antitumor properties (14), suggesting that metformin usage could expand beyond the treatment of type 2 diabetes (15). Daily doses of metformin are high (0.5–2.5 g day−1) and the vast majority pass through ...
In glioma and other tumors, the Warburg effect plays a crucial role in supporting rapid cell proliferation and tumor growth [10,11]. The phenomenon has become a significant area of research in cancer metabolism and represents a potential target for anti-cancer therapies. Fuentes-Fayos et al. ex...
Metformin is a strongly recommended first-line drug for the treatment of diabetes as well as a potential anti- aging medicine. Evidence from both clinical and pre- clinical studies supports the benefits of metformin in improving healthspan and expanding lifespan [9]. Moreover, metformin can ...