Clinically, collagen density in the lymph nodes may be a good marker for identifying lymph nodes that have been invaded by breast cancer cells.doi:10.1038/srep10002.Asif RizwanCamille BulteAnusha KalaichelvanMenglin ChengKristine GlundeScientific Reports...
The metastatic lymph-node ratio has important prognostic value in gastric cancer; this study focused on its significance in early gastric cancer. In total, 1,472 patients with early gastric cancer underwent curative gastrectomy between 1992 and 2001. Of these, 166 (11.3%) had histologically proven...
Nanoparticles have many potential benefits for diagnosing and treating metastatic cancer, including the ability to transport complex molecular cargoes to the major sites of metastasis, such as the lungs, liver and lymph nodes, as well as targeting to specific cell populations within these organs. ...
"Whencancer cellsspread in the body, often the first place they travel is the lymph node that drains the site of the primarytumor, but there has been controversy around the ability ofcellsfrom the lymph nodes to spread to organs such as the lung, liver, bone and brain—sites where the s...
Thus, the rational categorization of resected lymph nodes will help further improve therapeutic efficacy [1]. However, there are controversies in the classification of lymph node metastasis in gastric cancer. In Japan, the classification of lymph node metastasis is based on the anatomical station of...
Deciphering metastatic routes is critically important as metastasis is a primary cause of cancer mortality. In colorectal cancer (CRC), it is unknown whether liver metastases derive from cancer cells that first colonize intestinal lymph nodes, or whether such metastases can form without prior lymph no...
MLR was an independent prognostic factor on multivariate analysis, but the number of metastatic lymph nodes was not. Conclusions MLR can be a prognostic factor in patients who undergo radical resection for gastric cancer and can overcome the limitations of existing prognostic factors. This is a ...
Many studies have shown that the metastatic lymph node ratio, calculated by dividing the number of metastatic lymph nodes by the total number of lymph nodes, is an important prognostic factor in gastric cancer. In the present study, the applicability of the metastatic in the 1997 Tumor Node Met...
Metastatic/advanced stage breast cancer commonly called as stage IV breast cancer, wherein the cancer cells invade distant sites beyond the breast in proximity to auxiliary lymph nodes [2]. Most often, it spreads to bone, liver, lungs, brain and other organs. Sometimes, metastatic cancer...
The microenvironment of lymph node metastasized tumors (LNMT) determines tumor progression and response to therapy, but a systematic study of LNMT is lacking. Here, we generate single-cell maps of primary tumors (PTs) and paired LNMTs in 8 breast cancer