The most common sites of haematogenous metastasis were lung (75%), liver and bone (40%), soft tissue (34%), adrenal gland (22%), pleura (31%) and heart/pericard (16%). Brain metastases were seen in 15% of all RCC patients with metastasis (see Figure 1) and in 18.6% of ...
ICD-O-3/WHO 2008 between 2010-2015; (V) belonging to 1 of the 4 subtypes: HR+/HER2−, HR+/HER2+, HR−/HER2+, and HR−/HER2−; and (VII) either positive or negative metastasis status at diagnosis in lung, bone, liver, brain; (VIII) histopathological information on tumor ...
Racial parity in tumor burden, treatment choice and survival outcomes in men with prostate cancer in the VA healthcare system. Prostate Cancer Prostatic Dis. 2015;18(2):104-109. doi:10.1038/pcan.2014.51 PubMedGoogle ScholarCrossref 36. Freeman VL, Durazo-Arvizu R, Arozullah...
The tumor microenvironment reestablishment was also explored. Combined with immunogenic cell death (ICD) caused by chemotherapy drug DOX38, FD/DOX is expected to stimulate potent anti-tumor immune responses, contributing to the metastatic cancer treatment. 2. Materials and methods 2.1. Materials ...
and found that only 17% attended the outpatient PC appointment although nearly 57% were evaluated by the inpatient PC team during the last hospitalization prior to death [14]. Recently, a report focused on the integration of PC in hospitalized patients with metastatic tumor receiving CCT from Cal...
(skin) tumours Endocrine tumours Bone and soft tissue sarcoma tumours Other known primary tumours Data are presented as n (%) Men (n = 3344) 960 (28.7) 598 (17.9) 676 (20.2) 264 (7.9) 176 (5.3) 282 (8.4) 248 (7.4) 1 (\ 0.1) – 60 (1) 38 (1.1) 35 (1) 6 (0.2) Women...
bone metastatic tumors, and boost the tumor-infiltration of cytotoxic CD8+and CD4+T cells with little systemic toxicity in two breast cancer models. In summary, the artificially engineered macrophages hold considerable promise as controlled drug reservoirs and ICD-inducing carriers to achieve synchronous...
[DC], and T cells), depletion or inhibition of suppressor cell populations (tumor-associated macrophages [TAM], myeloid derived suppressor cells [MDSC], Tregs), and induction of immunogenic cell death (ICD), a stress response associated with release of danger-associated molecular patterns (DAMPs)...
Bone Research (2023) Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses Taghreed Hirz Shenglin Mei David B. Sykes Nature Communications (2023) Platinum-resistance in epithelial ovarian cancer: an interplay of epithelial–me...
Administration of radium-223 and the prognosis in Japanese bone metastatic castration-resistant prostate cancer patients: A large database study. Int. J. Urol. 2022, 29, 1079–1084. [Google Scholar] [CrossRef] [PubMed] Challita-Eid, P.M.; Satpayev, D.; Yang, P.; An, Z.; Morrison...