The prognosis of metastatic RCC is very poor, and the survival rate ranges from 10 months to one year1,2. According to the Memorial Sloan-Kettering Cancer Center (MSKCC) study, the average survival of patients post-nephrectomy followed by metastasectomy is approximately 30 months7.Amal Alrayes...
Predicting time-dependent survival probability of a breast cancer patient using information such as primary tumor size, grade, node spread status, and patient age at the time of surgery can be of immense help in managing life expectations and strategizing postoperative treatment. However, for moderate...
Breast cancer, a highly fatal disease due to its tendency to metastasize, is the most prevalent form of malignant tumors among women worldwide. Numerous studies indicate that breast cancer exhibits a unique predilection for metastasis to specific organs including the bone, liver, lung, and brain. ...
Purpose: Survival of metastatic breast cancer patient remains unknown and varies greatly from person to person. Thus, we aimed to construct a nomogram to quantify the survival probability of patients with metastatic breast cancer (MBC). Materials and methods: We had included 793 MBC patients and ...
The 5-year survival rate for localized breast cancer is 99%, but decreases to 80% once cells have reached the lymph nodes, and drops to 29% once metastases have formed in distant organs[1]. Triple-negative breast cancer (TNBC), which represents 10–15% of all breast cancers, is known ...
Here, we show that FER regulates breast cancer cell adhesion, migration and anoikis resistance, and is necessary for tumour growth and metastasis formation in mice. Moreover, FER expression is high in poorly differentiated breast carcinomas and independently predicts decreased patient survival. RESULTS...
The mortality of breast cancers has decreased by 34% and the five-year overall survival rate has increased to 90% since 19903; however, metastatic breast cancer remains difficult to cure. Despite the significant advances that have been achieved in understanding breast cancer metastasis in the past...
with HER2-positive cancer, it was found that the less AXL is present, the better the survival rate. Previously, researchers had linked the AXL protein to another type of cancer, triple negative breast cancer, but no one had examined its presence in HER2-positivecancerbefore Côté and his ...
Between 1987 and 1995, 52 breast cancer patients had a surgical resection of lung secondaries. In 40 patients, the diagnosis of metastatic breast cancer could be confirmed following pathological examination. Five-year survival rates of these 40 patients was 54 +/- 8% and 5-year disease free su...
Liquid biopsy-based technologies: a promising tool for biomarker identification in her2-low breast cancer patients for improved therapeutic outcomes Abstract: The molecular classification of breast cancer plays a pivotal role in developing personalized treatment strategies, with the aim of improving therapeut...