Introduction Metallo-beta-lactamases (MBLs) are responsible for resistance to almost all beta-lactam antibiotics. Found predominantly in Gram-negative bacteria, they severely limit treatment options. Understanding the epidemiology, risk factors, treatment, and prevention of infections caused by MBL-...
New Delhi Metallo-Beta-lactamases (NDMs) are amongst some of the most worrisome and prevalent MBLs. This family of MBLs is capable of hydrolyzing all generations of bicyclic beta-lactams. Among this family, NDM-1, NDM-4, and NDM-12 are key members. To combat these proteins, an inhibitor...
延长的光谱AmpC和梅塔洛betalactamases在沙雷氏菌属和Citrobacter在圆盘略计分析用试样的spp。 翻译结果5复制译文编辑译文朗读译文返回顶部 延长的光谱AmpC和metallobetalactamases在沙雷氏菌属和Citrobacter spp。 在圆盘略计分析用试样。 相关内容 anet,citizen 网,公民[translate] ...
Extended spectrum beta lactamases were screened by double disc synergism test (DDST) and Combination disc test (CDST). Strains resistant to carbapenems were further screened for metallo-尾-lactamases (MBLs) using EDTA- imipenem disc synergism test and modified Hodge test. 498 Gram negative strains...
We determined the prevalence of metallo-beta-lactamases (MBLs) produced by strains of Pseudomonas species isolated at the VU University Medical Center, in Amsterdam, The Netherlands, during 7 months of 2007. Of 328 patients, 2 (0.6%) carried a MBL positive Pseudomonas strain. This is the firs...
Metallo-β-lactamases (MBLs) represent the latest generation of β-lactamases. The structural diversity and broad substrate profile of MBLs allow them to confer resistance to most β-lactam antibiotics. To explore the evolutionary potential of these enzymes, we have subjected the Bacillus cereus MBL...
Poirel L, Pham JN, Cabanne L et al (2004) Carbapenem-hydrolysing metallo-beta-lactamases from Klebsiella pneumoniae and Escherichia coli isolated in Australia. Pathology 36:366–367Poirel L, Pham JN, Cabanne L, Gatus BJ, Bell SM, Nordmann P. Carbapenem-hydrolysing metallo-β-lactamases from ...
Metallo-beta-Lactamases (MBLs) are class B β-lactamases that hydrolyze almost all clinically-available β-lactam antibiotics. MBLs feature the distinctive αβ/βα sandwich fold of the metallo-hydrolase / oxidoreductase superfamily and possess a shallow active-site groove containing one or two ...
Environmental Microbiota Represents a Natural Reservoir for Dissemination of Clinically Relevant Metallo-尾-Lactamasesdoi:10.1109/TAC.1967.1098749... C Scotta,C Juan,G Cabot,... - 《Automatic Control IEEE Transactions on》 被引量: 0发表: 1967年 Metallo-beta-lactamase producers in environmental microbi...
metalloenzymesNew Delhi metallo-beta-lactamase (NDM) is a metallo-beta-lactamase able to hydrolyze almost all beta-lactams. Twenty-four NDM variants have been identified in >60 species of 11 bacterial families, and several variants have enhanced carbapenemase activity. Klebsiella pneumoniae and ...