Although some people think that the index is not suitable for clinical detection of bone disease, but some researchers think BTMs reduction may be diabetes mellitus type 1 warning, it may be diabetes mellitus type 1 patient with early bone change inspection index [123]. 3.7. Postoperative ...
Diabetes is a metabolic disease afflicting millions of people worldwide. A substantial fraction of world’s total healthcare expenditure is spent on treating diabetes. Hypoglycemia is a serious consequence of anti-diabetic drug therapy, because it induces metabolic alterations in the brain. Metabolic ...
thus unleashing antitumor immune responses [164]. In highly glycolytic tumors, Treg cells take up lactate through monocarboxylate transporter 1. Lactate promotes the nuclear translocation of nuclear factor of activated T cells (NFAT)-1, which increases the expression of PD-1 on Treg cells [165]...
thus unleashing antitumor immune responses [164]. In highly glycolytic tumors, Treg cells take up lactate through monocarboxylate transporter 1. Lactate promotes the nuclear translocation of nuclear factor of activated T cells (NFAT)-1, which increases the expression of PD-1 on Treg cells [165]...
23.Individualizing Therapies in Type 2 Diabetes Mellitus Based on Patient Characteristics: What We Know and What We Need to Know 机译:基于患者特征的2型糖尿病中的个性化疗法:我们所知道的以及我们需要知道的 作者:Robert J. Smith;David M. Nathan;Silva A. Arslanian;Leif Groop;Robert A. Rizza;Jerom...
type 2 diabetes mellitus(2型糖尿病) 研究背景 2型糖尿病(T2DM)的发病率不断增加,对全球医疗系统构成了重大挑战。 T2DM与加速的细胞老化有关,表现为组织完整性和功能的逐渐丧失。 细胞老化标志物在糖尿病患者的多种组织中增加,包括胰岛β细胞的衰老。 运动在T2DM的治疗和预防中至关重要,已被证明可以减缓多种老化...
Patients with obesity, type 2 diabetes mellitus (DM), and MetS have oversecretion of VLDL due to high plasma free fatty acid levels and high liver fat content (21). Elevated serum VLDL and LDL concentration has been linked to hepatic lobular inflammation, independent of steatosis (27). Furthe...
展开 关键词: RANDOMIZED CONTROLLED-TRIAL D-RECEPTOR GENE PROTEIN-KINASE-C TYPE-2 DIABETES-MELLITUS SERUM 25-HYDROXYVITAMIN D PLACEBO-CONTROLLED TRIAL MEDIATED GLUCOSE-UPTAKE NONSPECIFIC MUSCULOSKELETAL PAIN COMMUNITY-DWELLING WOMEN DOI: 10.1210/er.2012-1012 被引量: 392 年份...
Abstract Synovial fluid, blood, and urine biomarkers for articular cartilage function have been long sought as these markers are potentially more sensitive than clinical imaging to offer prognosis with respect to disease evolution and response to therapy. Many different biomarkers have been investigated ...
homeostasis model assessment of insulin resistance NGT: normal glucose tolerance OC: Osteocalcin OGTT: oral glucose tolerance test P1NP: Procollagen 1 Amino-terminal Propeptide TG: Triglycerides T2DM: Type 2 diabetes mellitus 2-h PG: 2 h plasma glucose WC: waist circumference ...