VDRs are expressed by all three major bone cell types: osteoclasts, osteoblasts, and osteocytes. VDRs are essential regulators of vitamin D metabolism. Hence, defects in the VDR gene results in hereditary vitamin D-resistant rickets, characterized by an impairment of a bone matrix mineralization ...
Metabolism of 25-hydroxyvitamin D 3 by microsomal and mitochondrial vitamin D 3 25-hydroxylases (CYP2D25 and CYP27A1): a novel reaction by CYP27A1[J] . Zufan Araya,Fardin Hosseinpour,Karl Bodin,Kjell Wikvall.BBA - Molecular and Cell Biology of Lipids . 2003 (1)...
Nutrition and Cancer LucieSafrhansova, ...JuliaStarkova, inInternational Review of Cell and Molecular Biology, 2022 5.1Cysteine metabolism Cysteine metabolismis closely linked tomethioninemetabolism. Cysteine is synthesized from methionine in four steps - the first two steps are part of the methionine ...
As antioxidant, vitamin E acts in cell membranes where prevents the propagation of free radical reactions, although it has been also shown to have pro-oxidant activity. Non-radical oxidation products are formed by the reaction between α-tocopheryl radical and other free radicals, which are ...
In addition, vitamin K has carboxylation-independent functions. Akin to ubiquinone, vitamin K acts as an electron carrier for ATP production in some organisms and prevents ferroptosis, a type of cell death hallmarked by lipid peroxidation. In this Perspective, we provide an overview of the diverse...
This Perspective provides a concise overview of the diverse functions of vitamin K in physiology and metabolism, including its recently discovered role in ferroptosis. Eikan Mishima Adam Wahida Marcus Conrad Perspective19 Jun 2023 Gut hormone co-agonists for the treatment of obesity: from bench to ...
Biotin in metabolism and molecular biology [Review] Biotin is a water-soluble vitamin required by all organisms by virtue of its essential role in carboxylation reactions. Although the metabolism and role of... McMahon,RJ - 《Annual Review of Nutrition》 被引量: 310发表: 2002年 Pyruvate carboxy...
HaCaT cell line as a model system for vitamin D3 metabolism in human skin. Synthesis and catabolism of calcitriol (1,25(OH)2D3) were studied using HaCaT cell line as a cell culture model. Our results indicate that stimulation of H... Lehmann,Bodo - 《Journal of Investigative Dermatology》...
From the Departments of Medicine and Cell Biology, Division of Endocrinology and Metabolism, The University of Alabama at Birmingham, Birmingham, Alabama... D Wang,TH Shin,JE Kudlow - 《Journal of Biological Chemistry》 被引量: 119发表: 1997年 The biochemistry and cell biology of aging: meta...
HJ Armbrecht,RK Nemani,N Wongsurawat - 《Advances in Molecular & Cell Biology》 被引量: 4发表: 1996年 Vitamin D Regulation of Energy Metabolism in Cancer Vitamin D exerts anti-cancer effects in recent clinical trials and preclinical models. The actions of vitamin D are primarily mediated throu...