HomoPesticides have the potential to leave harmful effects on humans, animals, other living organisms, and the environment. Several human metabolic proteins inhibited after exposure to organophosphorus pesticide
HumanCyc(Romeroet al., 2004): is a bioinformatics database that describes the human metabolic pathways and thehuman genome. By presenting metabolic pathways as an organizing framework for the human genome, HumanCyc provides the user with an extended dimension for functional analysis ofHomo sapiensat...
Human BAG-1/RAP46 protein is generated as four isoforms by alternative translation initiation and overexpressed in cancer cells. Oncogene 17, 981–989 (1998). CAS PubMed Google Scholar Calkhoven, C. F. et al. Translational control of SCL-isoform expression in hematopoietic lineage choice. ...
Arginine, a semi-essential amino acid, is critical for cell growth. Typically, de novo synthesis of arginine is sufficient to support cellular processes, however, it becomes vital for cancer cells that are unable to synthesise arginine due to enzyme defi
Key metabolic pathways were disrupted, with 39 differential metabolites identified. Notably, metabolites, such as L-homoarginine and diethanolamine, which were elevated in COPD–MS patients, showed strong correlations with DEGs involved in neutrophil pathways and immune checkpoint regulation. The study ...
because the metabolic networks of hosts registered in PHI-base may be not available in the KEGG database; specifically, we used the metabolic networks of Homo sapiens (human), Arabidopsis thali- ana (thale cress), and Drosophila melanogaster (fruit fly) for mammal, plant, and insect host spec...
compartmentalization has been developed through anchoring enzymes from metabolic pathways to sub-organelles to induce substrate channeling [18]. However, several substantial limitations might hinder its further application. Firstly, linking localization tags on enzymes may interfere with their structure and ...
Huguenin-Dezot N, Tang S, Suginta W, Paosawatyanyong B, Babu MM, Chin JW, Pakotiprapha D, Bhanthumnavin W, Uttamapinant C (2022) Discovery and genetic code expansion of a polyethylene terephthalate (PET) hydrolase from the human saliva metagenome for the degradation and bio-functionalizati...
hyopneumoniae swine host (Sus scrofa; TAX:9823) and 261 for human (Homo sapiens; TAX:9606) pathways is contained in the database. The polycyclic aromatic hydrocarbon degradation (00624) pathway was not present in strain 168. Strain 232, 7448 and J of M. hyopneumoniae had been reported to ...
MetaboAnalyst 3.0 (MetPA). The pathway libraries chosen were forHomo sapiens(human) andRattus norvegicus(rat). Fisher’s exact test was applied to perform an over-representation analysis, and relative betweenness centrality was chosen for pathway topology testing. Pathways with a raw p < 0.05...