MET基因是非小细胞肺癌的重要肿瘤驱动基因,针对MET 14外显子跳跃突变的靶向药物为患者带来新的治疗希望。虽然以tepotinib和沃利替尼等为代表的MET抑制剂显示出良好的抗肿瘤效果,但MET抑制剂的耐药不可避免。通过对HGF/MET信号通路的研究,不仅...
the drug. If drug molecules are present in the urine above the cut-off concentration of the test, they compete with the immobilized drug conjugate on the test region for limited antibody binding sites.This will prevent attachment of the antibody-colored particle ...
Co-Innovation rapid multi-drug test cup is a simple to administer, all-inclusive drug screen.with up to 18 drug assays and multiple configurations in one cup and result that can be photocopied. Product Details: Specimen: Urine Time to result:within 5 minutes Storag...
Drug nameCut off level(ng/ml)Drug nameCut off level(ng/ml) AMP(Amphetamine)1000MDMA(Ecstasy)500 THC(Marijuana)50BUP(Buprenorphine)10 COC (Cocaine)300EDDP(Methadone metabolite)100 PCP(Phencyclidine)25PPX (Propoxyphene)300 MOR(Morphine)300ETG(Ethylglucoronide)500 ...
Kinase inhibition was investigated using one of three assay formats: [33P]phosphoryl transfer, luciferase-coupled chemiluminescence, or AlphaScreen tyrosine kinase technology. Further assay details are provided in Supplementary Section. IC50 values were calculated by nonlinear regression analysis using XLFit...
″The National Cancer InstituteCancer DrugDiscovery and Development Program.(美国国家癌症研究所癌症药物的发现与开发项目)Seminars in Oncology 1992,19,622-638;Boyd,M.R.;Paull,K.D.Some Practical Considerations and Applications ofthe National Cancer Institute In Vitro Anticancer Drug DiscoveryScreen(美国...
controlled substance- a drug or chemical substance whose possession and use are controlled by law Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc. Translations Spanish / Español Select a language: ...
A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patientsdoi:10.1158/0008-5472.CAN-10-4433The emergence of drug resistance is a primary concern in any cancer treatment, including with targeted ...
The seven c-Met inhibitors consistently and significantly decreased the viability of ABHD5-knockdown HCT116 cells but had modest effects on control cells (Fig. 2c). The drug with the greatest percent inhibition in our screen, the highly potent and selective c-Met inhibitor, savolitinib, ...
DOA Multi-Drug Panel/ Device/Cup Multi-Drug One Step Drug Screen Test Panel DOA-124 to DOA-1124 Urine 2-12 Drugs 20 Test/ box DUD-124 to DUD-1124 2-10 Drugs Multi-Drug One Step Multi-Line Drug Screen Test Device DOA-125 to DOA-112...