Adult bone marrow (BM) is a rich source of mesenchymal stem cells. The aim of this study was to isolate and characterize MSCs derived from the BM of red pandas. Red panda BM-MSCs isolated from five individuals were fibroblast-like cells, similar to other species. Cultured BM-MSCs with ...
Table 1. Systemic characteristics and single-kidney function in study groups at 16 weeks Empty CellLeanMetSMetS + RASMetS + RAS + EVsMetS + RAS + IL-10 KD EVs Body weight (kg) 71.1 ± 4.0 93.4 ± 0.9∗ 92.4 ± 2.3∗ 90.6 ± 3.1∗ 86.9 ± 3.0∗ MAP (mm Hg) 102.8 ± 3....
We conclude that contact or factors from periodontal ligament induced mesenchymal stem cells to obtain periodontal-ligament-like characteristics. Importantly, analysis of the data suggests the feasibility of utilizing mesenchymal stem cells in clinical applications for repairing and/or regenerating periodontal...
such as the liver, primarily because the structural characteristics of the lung microvasculature cause the majority of MSCs to become sequestered there.33However, the population of MSCs residing in the lungs diminishes due to increased permeability under injured ...
Bone marrow mesenchymal stromal/stem cells (MSCs) are a heterogeneous population that can self-renew and generate stroma, cartilage, fat, and bone. Although a significant progress has been made toward recognizing about the phenotypic characteristics of MSCs, the true identity and properties of MSCs ...
Connick P, Kolappan M, Patani R, Scott MA, Crawley C, He XL,et al. The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcome assessments.Trials2011;12: 62. ...
they have a wide range of prospective therapeutic applications with advantages over cell therapy. We describe some characteristics of MSC-EVs, and discuss their role in immune regulation and regeneration, with emphasis on the molecular mechanism and application of MSC-EVs in the treatment of fibrosis...
In recent years, human mesenchymal stem cells (MSC) have been extensively studied. Their key characteristics of long-term self-renewal and a capacity to differentiate into diverse mature tissues favor their use in regenerative medicine a... R Anzalone,ML Iacono,S Corrao,... - 《Stem Cells &...
New human nonimmortalized fibroblast-like cell lines were derived from various sources: from embryonic stem cells (ESCs) (the SC5-MSC and SC3a-MSC lines), from bone marrow of a 5- to 6-week-old fetus (the FetMSC line), and from foreskin of a 3-year-old child (the FRSN line). All...
MAPC have been shown to produce cells with characteristics of visceral mesoderm, neuroectoderm, or endoderm. When injected into an early blastocyst a single MAPC contributed to the development of various tissues [3]. Recently, Kogler et al. have described another subset of MSC derived from ...