然而其受体识别的分子机制以及广泛宿主识别能力的关键因素尚未揭示。 2024年6月14日,中国科学院微生物研究所高福院士团队在EMBO Reports上发表题为Molecular basis for receptor recognition and broad host tropism for merbecovirus MjHKU...
总结: 本文以GEO数据库下载的数据为出发点,利用生物信息学分析方法分析了3种病毒中的circRNAs,研究了它们的表达,功能等特征,并将结果存储在VirusCircbase数据库中供查询,为冠状病毒的研究提供了新思路、新材料。 能够纯生信发8分的文章,我们认为以下为其加分点,可供借鉴! 1, 冠状病毒,研究热点 2, VirusCircbase数...
截至2022年12月,世界卫生组织(WHO)报告实验室确诊的中东呼吸综合征冠状病毒(Middle East respiratory syndrome coronavirus,MERS-CoV)感染2603例,死亡935例,死亡率为36%。然而,目前还没有针对MERS-CoV的疫苗,这导致MERS-CoV的防控变得困难...
MERS-CoV的功能受体是二肽基肽酶4(DPP4)。 (Ref: Nour Ramadan, Houssam Shaib.Middle East respiratory syndrome coronavirus (MERS-CoV): A review.GERMS.2019) MERS-CoV 相关产品列表 货号抗原表达宿主标签结合活性 40068-V08B NucleocapsidInsectHis
An electrochemical immunosensor for the corona virus associated with the Middle East respiratory syndrome using an array of gold nanoparticle-modified carbon electrodes这篇文献的标题 2021-11-07 回复喜欢关于作者 PalmSens电化学 回答1 文章123 关注者3,105 关注他发私信 ...
β-coronavirus: not the same virus as SARS, but related. Similar to other coronavirus described in bats. MERS-CoV: dromedary camels clearly established as a host; positive specimens are known dating at least to the early 1990s. Also seen in bats. Believed to be mostly a re...
The virus primarily causes respiratory failure in affected patients, but can also sometimes cause renal failure. The main reservoir of this virus is dromedary camels. Although a lot is known about the diseases pattern, pathogenesis, and immunity of MERS-CoV infection in humans, very little is ...
virus, Streptococcus pneumoniae, Hemophilus influenzae, Staphylococcus aureus, and Legionella pneumophila). This evaluation should be based on clinical presentation and epidemiologic and surveillance information. Testing for MERS-CoV and other respiratory ...
RNA（noncoding RNA）。例如，SARS-CoV编码的3个small RNAs与肺致病感染相关；SARS-CoV-2包含许多未知ORFs。因此，病毒编码非编码RNAs在感染过程中起着重要作用。环状RNAs（circRNA）是一类共价闭合长非编码RNA，没有3’ployA尾和5’cap。CircRNA主要通过3种机制产生：互补序列介导的环化，RNA结合蛋白驱动的环化和...
"In the absence of qualitative laboratory data from well-documented MERS cases, most of these considerations were up to now made upon an assumed analogy to SARS. However, we're now finding that certain elementary traits of the MERS virus appear to be different to SARS." ...